RecruitingNot ApplicableNCT05579470

Expanding Medication-Assisted Therapies in Central Asia


Sponsor

Yale University

Enrollment

900 participants

Start Date

Aug 7, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Central Asia (CA) represents the most rapidly growing HIV epidemic region worldwide, concentrated in people who inject drugs (PWID) and their sexual partners, and scaling up opioid agonist therapies (OAT) in this region is the most cost-effective strategy to prevent new HIV infections, and more effective when combined with antiretroviral therapy (ART). The investigators propose to use the Network for the Improvement of Addiction Treatment (NIATx) implementation strategy to scale-up OAT in three diverse Central Asian countries (Kazakhstan, Kyrgyzstan, Tajikistan) and guided by the Exploration-Planning-Implementation-Sustainment (EPIS) framework. Understanding the trajectories of implementation and scale-up in this context may emerge through creating communities of practice, especially when cohesion and competence evolves, and may guide other healthcare delivery challenges in the region (e.g., HIV, TB); as well as build important regional expertise and understanding implementation trajectories should help support OAT program sustainability.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at how to expand access to medication-assisted treatment (MAT) for opioid dependence in Central Asia. Researchers are surveying people who inject drugs, those already receiving treatment, and healthcare workers to understand barriers and improve opioid treatment programs in the region. **You may be eligible if...** - You are 18 or older - You meet clinical criteria for opioid dependence - You are either new to opioid treatment or started treatment less than 90 days ago (for patient participants) - OR you currently work as a healthcare provider at an opioid treatment site (for staff participants) **You may NOT be eligible if...** - You do not meet the criteria for opioid dependence - You have been on opioid treatment for more than 90 days (for some parts of the study) - You are under 18 Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALNIATx

For each country, the learning collaborative will be comprised of a Chief Narcologist from each region where the investigators will initially train them and the coaches using all the tools from the NIATx Academy (2-3-day training). The national coach for each country will receive ongoing and in-depth coaching from a US-based super coach. A nationwide Nominal Group Technique (NGT) will be conducted to assess barriers and potential targets to guide decision-making about changes. At the end of the initial meeting, each Chief Narcologist (CN) will be able to identify a change target for Plan, Do, Study, Act (PDSA) (entry, retention) and create a Change Project Form to state what will be done (e.g. flowcharting), who is involved (team), what are the measures and timeframe (\<4 weeks).


Locations(4)

Yale University

New Haven, Connecticut, United States

Columbia University Global Health Research Center of Central Asia

Almaty, Kazakhstan

Den Sooluk Nuru

Bishkek, Kyrgyzstan

Institute for International Health and Education

Dushanbe, Tajikistan

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NCT05579470


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