RecruitingPhase 1Phase 2NCT05584800

Study of ZGGS18 in Patients With Advanced Solid Tumors

A Phase I/II Dose Escalation, Tolerability, Safety, Pharmacokinetics and Multiple Cohort Expansion Study of ZGGS18 in Patients With Advanced Solid Tumors


Sponsor

Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Enrollment

222 participants

Start Date

Nov 15, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

A clinical study to assess dose escalation, tolerance, safety, pharmacokinetics, and multi cohort expansion of ZGGS18 in patients with advanced solid tumors


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called ZGGS18 for Injection and a biological treatment called ZGGS18 for Injection for people with advanced solid tumor. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALZGGS18 for Injection

0.3 mg/kg, 1 mg/kg, 3 mg/kg, 6 mg/kg, 10 mg/kg, 15 mg/kg and 20 mg/kgof ZGGS18,intravenous infusion, once every 2 weeks.

BIOLOGICALZGGS18 for Injection

Recommended Phase 2 Dose (RP2D) (to be determined) of ZGGS18,intravenous infusion, once every 2 weeks.


Locations(1)

Chinese PLA General Hospital

Beijing, Beijing Municipality, China

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NCT05584800


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