A Novel Oral Synbiotic Formula in Reducing Advanced Adenoma Recurrence and Colorectal Neoplasia-related Bacterial Gene Markers

This study is testing a synbiotic supplement (a combination of probiotics and prebiotics) taken by mouth to see if it can reduce the chance of colon polyps coming back after they have been removed. It also measures changes in gut bacteria linked to colorectal cancer risk. **You may be eligible if...** - You are 18–90 years old - You recently had advanced colorectal polyps (adenomas or early-stage cancer) removed via colonoscopy - Your colonoscopy was complete and your bowel was well-prepared - All visible polyps were completely removed **You may NOT be eligible if...** - There are still remaining polyps that were not removed - You have had prior colon surgery - You have a hereditary colorectal cancer syndrome or inflammatory bowel disease - You are pregnant or breastfeeding - You have a weakened immune system Talk to your doctor to see if this trial is right for you.