Effect of Lithium Carbonate on Postoperative Sleep and Cognitive Function in Patients Undergoing Heart Valve Surgery With Cardiopulmonary Bypass
China Medical University, China
62 participants
Jul 1, 2023
INTERVENTIONAL
Conditions
Summary
It has been proved that lithium carbonate can prolong slow wave sleep with few or no side-effects. The aim of the present study is to evaluate postoperative sleep quality of patients undergoing heart valve surgery with cardiopulmonary bypass taken 250mg lithium carbonate after surgery.
Eligibility
Inclusion Criteria3
- Ethnic Chinese;
- Age, 18 to 65 years old;
- Patients undergoing heart valve surgery with cardiopulmonary bypass
Exclusion Criteria10
- Preoperative Pittsburgh Sleep Quality Index global scores higher than 6
- Cognitive difficulties
- Partial or complete gastrectomy
- Previous esophageal surgery
- Previous treated by radiotherapy or surgery
- Inability to conform to the study's requirements
- Body mass index exceeding 30 kg/m2
- Deprivation of a right to decide by an administrative or juridical entity
- Ongoing participation or participation in another study <1 month ago
- Recent (< 3 months prior) use of antibiotics, probiotics, prebiotics, symbiotics, hormonal medication, laxatives, proton pump inhibitors, insulin sensitizers or traditional Chinese medicine
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Patients undergoing heart valve surgery withcardiopulmonary bypass will take 250mg lithium carbonate
Patients undergoing heart valve surgery withcardiopulmonary bypass will take 500mg calcium carbonate
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05593627