Cilostazol and Methotrexate in Rheumatoid Arthritis

This study is testing whether adding cilostazol (a drug normally used to improve blood flow) to methotrexate (a common rheumatoid arthritis medication) can improve joint symptoms in people with active rheumatoid arthritis. Researchers think cilostazol may have additional anti-inflammatory benefits. **You may be eligible if...** - You are 18–60 years old - You have active rheumatoid arthritis that is not in remission (DAS-28 score above 2.6) - You are already taking methotrexate - You may also be taking low-dose anti-inflammatory medications or low-dose steroids (under 15 mg prednisolone) **You may NOT be eligible if...** - You have diabetes, heart failure, serious heart disease, arrhythmia, high blood pressure, or severe anemia - You take blood thinners, anticoagulants, or low-dose aspirin - You have kidney or liver disease - You take oral steroids at a dose higher than 15 mg prednisolone Talk to your doctor to see if this trial is right for you.