RecruitingNCT05596773

Community-Based Chronic Disease Care in Rural Lesotho

Community-Based Chronic Disease Care in Rural Lesotho: The ComBaCaL Cohort Study


Sponsor

University Hospital, Basel, Switzerland

Enrollment

17,500 participants

Start Date

Feb 22, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This ComBaCaL cohort study is to assess the impact of community-based, lay-led chronic disease screening and care interventions in rural Lesotho. It aims to establish a prospective research and service delivery platform in rural Lesotho that is managed by eHealth-supported Chronic Care Village Health Worker (CC-VHWs) providing regular chronic disease screening, monitoring and referral services. The implementation outcomes of the cohort as well as the effect of the cohort activities on disease-specific care cascades will be assessed. Subsequently, nested trials to assess the effectiveness of specific chronic disease control interventions will be developed. Measurements and data entry will be conducted by CC-VHWs. The CC-VHWs will be equipped with the essential tools required for chronic disease monitoring in the community (i.e. BP machines, scales, measuring band, glucometers, and urine dipsticks). They will undergo a theoretical and practical training covering all aspects required for correct data collection and chronic disease screening, diagnosing, referral and counselling services. At every visit, the CC-VHW will screen participants for warning signs and symptoms (i.e. shortness of breath, severe headache, chest pain, new-onset confusion, impaired consciousness, severely impaired general state of health) and refer participants to the closest health centre in case of any danger-sign. The CC-VHWs will be continuously monitored and supervised by health centre nurses of the respective village's catchment area, mainly through direct interaction during monthly VHW meetings and by CC nurses through field visits, remote interaction via phone calls or messages sent via the ComBaCaL app and through direct contact during the monthly VHW meetings at the health centre. The CC-VHWs are embedded within the Lesotho MoH VHW program and may during the project period be trained and equipped to provide further routine services in their communities.


Eligibility

Plain Language Summary

Simplified for easier understanding

This study tests a community-based model for managing chronic diseases like HIV and diabetes in rural villages in Lesotho, Africa. Specially trained community health workers would visit people at home instead of requiring them to travel to a clinic. **You may be eligible if...** - You live in a rural village in Lesotho with 40 to 100 households - Your village chief has given consent for the village to participate - You have a chronic condition such as HIV, diabetes, or hypertension that is being managed **You may NOT be eligible if...** - Your village is too large or too small to participate - Village consent has not been obtained - You require hospital-level care that cannot be managed in the community Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(2)

Solidarmed Lesotho

Maseru, Lesotho

Division of Clinical Epidemiology, University Hospital Basel, University of Basel

Basel, Switzerland

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NCT05596773