RecruitingNot ApplicableNCT05600738

Network Effects of Therapeutic Deep Brain Stimulation


Sponsor

The University of Texas Health Science Center, Houston

Enrollment

25 participants

Start Date

Aug 26, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to map the acute, short-term cortical evoked responses to thalamic electrical stimulation in persons with intractable epilepsy


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • diagnosis of Epilepsy
  • undergoing neuromodulation therapy with clinically implanted neuromodulation devices (DBS, RNS)
  • followed in the outpatient epilepsy clinic

Exclusion Criteria4

  • pregnant women
  • active psychosis, major depression, or suicidal ideation in the preceding year
  • Intelligence quotient (IQ) less than 70 as measured by clinical neuropsychological evaluation
  • Do not agree to share their medical records for research purposes

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Interventions

DEVICERNS/DBS activation

This will be performed to study the EEG responses to DBS/RNS stimulation electrical pulses. The stimulation frequencies will be sequentially increased and each stimulation will last for 2 minutes.There will be a 1-2 minute wash out period after each trial.


Locations(1)

The University of Texas Health Science Center at Houston

Houston, Texas, United States

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NCT05600738


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