VCA Regimen Followed by D-MAG Regimen on the Treatment of Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)

This study tests a combination chemotherapy approach (VCA followed by D-MAG regimen) for older adults with newly diagnosed acute myeloid leukemia (AML) who cannot tolerate standard intensive chemotherapy due to age or other health conditions. The goal is to find an effective but more tolerable treatment option for this vulnerable population. **You may be eligible if...** - You are 60 or older - You have been newly diagnosed with AML (not APL/M3 type) - You cannot receive standard intensive chemotherapy (due to age, other health conditions, or your preference) - Your kidneys and liver are functioning adequately - Doctors expect you to live at least 3 more months **You may NOT be eligible if...** - You have the APL (M3) subtype of AML - You have severe kidney or liver problems - You have serious heart conditions or uncontrolled infections - You have previously received treatment for this AML Talk to your doctor to see if this trial is right for you.