RecruitingPhase 4NCT05605639

Phrenic Nerve Infiltration in Neck Pain

Phrenic Afferences In Organic and Metabolic Illness: Central Sensitization


Sponsor

University of Seville

Enrollment

60 participants

Start Date

Nov 17, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Neck pain frequently present comorbidities in peridiaphragmatic organs. The innervation of these organs include the phrenic nerve. It is known that peridiaphragmatic organs trigger referred pain in the neck area. As well, previous studies have shown that visceral disorders increase sensitization in somatic tissues. This study aims to analyze the ability of phrenic nerve infiltration to diminish sensitization and improve neck symptoms in the absence of neurological, traumatic or infectious pathology that justifies the pain, by means of a randomized controlled trial.


Eligibility

Min Age: 18 YearsMax Age: 64 Years

Inclusion Criteria4

  • Over 18 and under 64 years old
  • Patients attending to the physician or physical therapist with a main complaint of neck pain
  • Presentation of any peridiaphragmatic visceral disorder.
  • That the subject agrees to participate in the project by signing the informed consent.

Exclusion Criteria8

  • Illness of neurological, traumatic, oncological, infectious or rheumatic (fibromyalgia, ankylosing spondylitis...) origin.
  • Uncooperative subject.
  • Severe psychiatric illness.
  • Loss of Cognitive Ability.
  • Contraindication to infiltration of the phrenic nerve.
  • History of head, spinal or upper limb surgery
  • History of infiltration for the neck pain in the previous 3 months
  • History of physical therapy for the neck pain in the previous 30 days

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Interventions

DRUGBupivacaine

The experimental intervention will consist of ultrasound-guided anesthetic blockade of the phrenic nerve at the laterocervical supraclavicular level with 1 ml of lidocaine without vasoconstrictor 2% to infiltrate the skin and 3ml of bupivacaine without vasoconstrictor 0.25% for neural blockade, making the local anesthetic surround the nerve between the anterior scalene muscle and the sternocleidomastoid muscle.

OTHERPlacebo (physiological saline serum infiltration)

The placebo intervention will be similar in relation to 2% lidocaine without vasoconstrictor for the skin, but an ultrasound-guided puncture will be performed at the level of the subcutaneous cellular tissue by injecting 3 ml of physiological saline.


Locations(2)

Nacho Navarro Fisioterapia

Dos Hermanas, Seville, Spain

Crux Roxa

Seville, Spain

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NCT05605639


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