A First in Human Study of AUR 103 Calcium to Evaluate Safety, Pharmacokinetics and Pharmacodynamics

This is the first human study of a new drug called AUR103, testing its safety, how the body processes it, and early signs of whether it works. It is open to adults with advanced solid tumors (Part 1) or acute myeloid leukemia (Part 2). **You may be eligible if...** - You are 18 years or older - You have a confirmed solid tumor (Part 1) that has not responded to at least 2 prior lines of treatment, OR - You have acute myeloid leukemia (Part 2) meeting specific criteria - You are willing and able to comply with all study visits and procedures **You may NOT be eligible if...** - You have not yet tried at least 2 standard therapies - You have significant organ dysfunction, active infections, or serious heart conditions - You are pregnant or breastfeeding (check with your doctor for full exclusion details) Talk to your doctor to see if this trial is right for you.