RecruitingNCT05609318
Imaging Intravenous Iron
Study of Tissue Iron Uptake in Iron-Deficient Patients Receiving Intravenous Iron Replacement Therapy: A Prospective Observational Study (STUDY)
Sponsor
University of Oxford
Enrollment
12 participants
Start Date
Oct 29, 2022
Study Type
OBSERVATIONAL
Conditions
Summary
The aim of this study is to track where the iron goes in different tissues in the hours, days and weeks after an intravenous iron infusion. We will track iron in tissues using MRI relaxometry parameters R1/R2/R2\* which are well established as accurate indicators of tissue iron content.
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- Participant is willing and able to give informed consent for participation in the study.
- Aged 18 years or above.
- Anaemia (haemoglobin less than 120g/L for women and less than 130g/L for men) and/or confirmed iron deficiency (ferritin less than 100mcg/L and/or transferrin saturation less than 20%).
- Scheduled to receive intravenous iron for correction of iron deficiency.
Exclusion Criteria6
- Any MRI incompatible implants (e.g. cardiac, neuro, ocular implants, surgical clips, aneurysm clips, shrapnel/bullets)
- Pregnant or lactating participant
- Acute decompensated heart failure
- Unstable clinical status
- Any other medical conditions which would influence the reliability of the study results determined by the investigators.
- Any other contraindication to MRI to be confirmed by the qualified MRI operator, e.g. tattoos containing traces of metal.
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05609318
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