Pentoxifylline as an Adjunct Therapy for Patients With Eisenmenger Syndrome

This study tests pentoxifylline — a drug that improves blood flow — as an add-on treatment for people with Eisenmenger syndrome, a serious complication of congenital heart disease where abnormal blood flow in the heart has led to severe pulmonary hypertension. **You may be eligible if...** - You have been diagnosed with Eisenmenger syndrome - Your functional class is WHO II, III, or IV for pulmonary hypertension - You may or may not be on anticoagulation (blood thinners like warfarin) **You may NOT be eligible if...** - You are currently hospitalized - You have a history of significant or repeated bleeding - You have major serious conditions requiring specific treatments - You are a candidate for any surgery (other than dental) - You have active systemic infection or inflammatory disease - You have low platelet counts (thrombocytopenia) Talk to your doctor to see if this trial is right for you.