RecruitingNCT05612100

Endocrine Therapy-Induced Alopecia in Postmenopausal and Premenopausal Female Breast Cancer Patients

Endocrine Therapy-Induced Alopecia Natural History Evaluation Among Female Breast Cancer Survivors


Sponsor

Mayo Clinic

Enrollment

170 participants

Start Date

Jul 6, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

This study evaluates endocrine therapy-induced alopecia among postmenopausal and premenopausal female patients with breast cancer. Alopecia is one of the most feared side effects of cancer-directed therapy, causing distress in women starting treatment for breast cancer. While alopecia is a well-known side effect of many chemotherapy drugs, it has also been reported by women undergoing endocrine therapy. Despite the frequent reports of alopecia related to endocrine therapy, hair loss is rarely reported as a side effect of endocrine therapy and the exact characterization of alopecia is not well understood. By having postmenopausal and premenopausal breast cancer patients describe their hair loss symptoms experienced while undergoing endocrine therapy, researchers may be able to better characterize the incidence, timing, duration, and severity of alopecia and whether the different types of endocrine therapy cause more or less trouble in this regard.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tracks hair loss caused by hormone-blocking medications (endocrine therapy) used to treat breast cancer — such as aromatase inhibitors or tamoxifen — to better understand how common it is and how it affects patients' quality of life. **You may be eligible if...** - You are 18 years or older - You are a woman diagnosed with breast cancer being treated with curative intent - You are receiving endocrine therapy (hormone-blocking treatment), or CDK4/6 inhibitors (a targeted therapy) - You are willing to complete questionnaires every 3 months - You fit into one of the study's 5 patient groups **You may NOT be eligible if...** - You are not receiving endocrine therapy or CDK4/6 inhibitors - You are unable or unwilling to complete the questionnaires within the required timeframes - You do not provide informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERElectronic Health Record Review

Ancillary studies

OTHERQuestionnaire Administration

Complete alopecia questionnaires

OTHERSurvey Administration

Complete alopecia surveys


Locations(23)

Mayo Clinic Health System in Albert Lea

Albert Lea, Minnesota, United States

Essentia Health Baxter Clinic

Baxter, Minnesota, United States

Sanford Joe Lueken Cancer Center

Bemidji, Minnesota, United States

Essentia Health Saint Joseph's Medical Center

Brainerd, Minnesota, United States

Essentia Health - Deer River Clinic

Deer River, Minnesota, United States

Essentia Health Saint Mary's - Detroit Lakes Clinic

Detroit Lakes, Minnesota, United States

Essentia Health Cancer Center

Duluth, Minnesota, United States

Essentia Health Ely Clinic

Ely, Minnesota, United States

Essentia Health - Fosston

Fosston, Minnesota, United States

Fairview Grand Itasca Clinic & Hospital

Grand Rapids, Minnesota, United States

Essentia Health Hibbing Clinic

Hibbing, Minnesota, United States

Fairview Range Medical Center

Hibbing, Minnesota, United States

Essentia Health - International Falls Clinic

International Falls, Minnesota, United States

Mayo Clinic Health Systems-Mankato

Mankato, Minnesota, United States

MMCORC CentraCare Monticello Cancer Center

Monticello, Minnesota, United States

Essentia Health Moose Lake

Moose Lake, Minnesota, United States

Essentia Health - Park Rapids

Park Rapids, Minnesota, United States

Fairview Northland Medical Center

Princeton, Minnesota, United States

Mayo Clinic in Rochester

Rochester, Minnesota, United States

Essentia Health Sandstone

Sandstone, Minnesota, United States

Sanford Health Thief River Falls

Thief River Falls, Minnesota, United States

Essentia Health Virginia Clinic

Virginia, Minnesota, United States

Sanford Health Worthington

Worthington, Minnesota, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05612100


Related Trials