Observational Study About Patients Diagnosed With NAFLD
Study on the Characteristic, Therapy and Prognosis of Patients With Nonalcoholic Fatty Liver Disease
Xiangya Hospital of Central South University
500 participants
Apr 27, 2022
OBSERVATIONAL
Conditions
Summary
Nonalcoholic fatty liver disease (NAFLD) is the most common condition affecting the liver, owing to its association with obesity and the metabolic syndrome. The largest study to date using magnetic resonance spectroscopy to quantify liver triglyceride (TG) content showed that approximately 33% of individuals have hepatic steatosis. NAFLD encompasses a continuum of histological findings that starts with steatosis that can progress to nonalcoholic steatohepatitis (NASH), which is characterized by inflammation and cell death, and eventually cirrhosis. Given the large number of individuals afflicted with this condition, there is a clear need to develop effective and safe therapies to treat NAFLD.
Eligibility
Inclusion Criteria1
- \. patients diagnosed with nonalcoholic fatty liver disease
Exclusion Criteria4
- patients suspected of excessive alcohol consumption
- malignant tumors, dementia, active tuberculosis, AIDS, organ failure, pregnancy or breastfeeding, etc cannot cooperate with the investigation
- incomplete data such as HBV serological results and abdominal ultrasound results
- patients who refuse to sign informed consent
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05625750