RecruitingNCT05626296
Molecular Network Characteristics of Phlegm-heat Syndrome in Ischemic Stroke Based on Multi-omics Integrated Analysis
Sponsor
Dongzhimen Hospital, Beijing
Enrollment
24 participants
Start Date
Nov 14, 2022
Study Type
OBSERVATIONAL
Conditions
Summary
The molecular characteristics of ischemic stroke with phlegm-heat syndrome and candidate biomarkers were identified based on multi-omics data. The main purpose of this study is to validate the molecular characteristics and biomarkers of phlegm-heat syndrome in ischemic stroke, and to demonstrate the association of biomarkers with clinical outcomes.
Eligibility
Min Age: 50 YearsMax Age: 80 Years
Inclusion Criteria5
- Acute ischemic stroke, were confirmed by magnetic resonance imaging (MRI).
- Symptom onset within 72 hours.
- Diagnosis of phlegm-heat syndrome or non-phlegm-heat syndrome.
- Male or female ≥ 50 years and ≤ 80 years.
- With written informed consent.
Exclusion Criteria5
- Planned or already receiving intravenous thrombolysis or endovascular treatment.
- Acute infectious diseases or acute exacerbations of chronic diseases within one month before enrollment.
- Patients with previous stroke.
- Renal or hepatic insufficiency, tumors, immune diseases, severe underlying diseases.
- Other conditions that may affect the collection and evaluation of clinical information (e.g., severe aphasia, mental illness).
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05626296
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