RecruitingNCT05632497

Alteration of Symbiosis Intestinal Microbiota on Patients With Anorexia Nervosa

Study of Translational Process of Relationship Between Intestinal Microbiota of Dysbiosis and the Psychic Symptoms of Anorexia Nervosa (Eating Disorders and Anxio-depression Disorders)

Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

120 participants

Start Date

May 23, 2024

Study Type

OBSERVATIONAL

Conditions

Dysbiosis Anorexia Nervosa Anxious Depression

Summary

The purpose of this study will be to study the association between the level of psychic symptomatic of anorexia nervosa (AN) (intensity of food restriction, symptoms of anxiety and depression) and alteration of host environment symbiosis and the mechanism (dysbiosis of intestinal microbiota, increase of intestinal permeability, immunity alteration and low-grade inflammation).

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study investigates how the gut bacteria (microbiome) in people with anorexia nervosa change during nutrition rehabilitation in a hospital setting. Understanding this connection could lead to better treatments for anorexia. **You may be eligible if...** - You are 18 years or older - You have been diagnosed with anorexia nervosa (based on international diagnostic criteria) - Your body mass index (BMI) is below 15 — indicating severe underweight - You are being hospitalized for nutritional rehabilitation - You have health insurance coverage **You may NOT be eligible if...** - You do not meet the clinical criteria for anorexia nervosa - You are not being hospitalized for nutritional rehabilitation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALStool and blood samples

Stool and blood samples

Locations(1)

Service de Nutrition Clinique, Hôpital Paul Brousse (APHP)

Villejuif, France

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NCT05632497

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