RecruitingPhase 3NCT05633654

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

A Randomized, Open-label, Phase 3 Study of Adjuvant Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy

Sponsor

Gilead Sciences

Enrollment

1,514 participants

Start Date

Dec 12, 2022

Study Type

INTERVENTIONAL

Conditions

Triple-Negative Breast Cancer

Summary

The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is effective and safe compared to the treatment of physician's choice (TPC) which includes either pembrolizumab or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after surgery and pre-surgical treatment.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing whether sacituzumab govitecan plus pembrolizumab is better than standard treatment for triple-negative breast cancer (TNBC) patients who had cancer remaining in the breast or lymph nodes after pre-surgery chemotherapy. **You may be eligible if...** - You are over 18 with residual invasive TNBC after neoadjuvant therapy and surgery - Your cancer is confirmed triple-negative (ER/PR ≤10%, HER2-negative) - Surgery removed all visible disease and you have recovered - You have had appropriate radiation if indicated and recovered from it - Your overall health is good (ECOG 0–1) with adequate organ function **You may NOT be eligible if...** - You have stage IV (metastatic) breast cancer or any prior invasive breast cancer - You have received prior immune checkpoint therapy (e.g., anti-CTLA-4, OX-40), anti-HER2 agents, or long-term hormone therapy - There is any sign that the cancer has returned - You have not submitted required tissue samples for analysis Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSacituzumab govitecan-hziy (SG)

Administered intravenously

DRUGPembrolizumab

Administered intravenously

DRUGCapecitabine

Tablets administered orally

Locations(350)

Alabama Oncology

Birmingham, Alabama, United States

Clearview Cancer Institute

Huntsville, Alabama, United States

Palo Verde Hematology Oncology

Glendale, Arizona, United States

Mayo Clinic Hospital

Phoenix, Arizona, United States

Arizona Oncology Associates

Prescott Valley, Arizona, United States

Alta Bates Summit Medical Center

Berkeley, California, United States

Community Cancer Institute

Clovis, California, United States

PIH Health Whittier Hospital

Downey, California, United States

Compassionate Cancer Care Medical Group - Inc

Fountain Valley, California, United States

Los Angeles Cancer Network

Los Angeles, California, United States

USC Norris Comprehensive Cancer Center

Los Angeles, California, United States

Cedars-Sinai Cancer at Beverly Hills

Los Angeles, California, United States

Hoag Memorial Hospital Presbyterian

Newport Beach, California, United States

Emad Ibrahim, MD, INC

Redlands, California, United States

Sutter Institute for Medical Research

Sacramento, California, United States

City of Hope (Duarte)

San Francisco, California, United States

UCSF Medical Center

San Francisco, California, United States

Sansum Clinic

Santa Barbara, California, United States

Stockton Hematology Oncology Medical Group

Stockton, California, United States

University of Colorado Cancer Center

Aurora, Colorado, United States

Norwalk Hospital

Danbury, Connecticut, United States

Stamford Hospital

Stamford, Connecticut, United States

MedStar Georgetown University Hospital

Washington D.C., District of Columbia, United States

MedStar Washington Hospital Center

Washington D.C., District of Columbia, United States

Morton Plant Hospital - Bay Care

Clearwater, Florida, United States

University of Florida

Gainesville, Florida, United States

Mayo Clinic Florida

Jacksonville, Florida, United States

Cancer Specialists of North Florida

Jacksonville, Florida, United States

Jupiter Medical Center

Jupiter, Florida, United States

Mount Sinai Comprehensive Cancer Center

Miami Beach, Florida, United States

Midland Florida Clinical Research Center, L

Orange City, Florida, United States

Orlando Health

Orlando, Florida, United States

Cancer Care Centers of Brevard, Inc

Palm Bay, Florida, United States

Memorial Healthcare System

Pembroke Pines, Florida, United States

Sacred Heart Medical Oncology Group

Pensacola, Florida, United States

Sylvester Comprehensive Cancer Center

Plantation, Florida, United States

Cleveland Clinic Florida, Martin North Hospital

Stuart, Florida, United States

St. Joseph's Hospital

Tampa, Florida, United States

Weston Hospital

Weston, Florida, United States

University Cancer & Blood Center, LLC.

Athens, Georgia, United States

Piedmont Cancer Institute

Atlanta, Georgia, United States

Northside Hospital

Atlanta, Georgia, United States

Northwest Georgia Oncology Centers, PC

Marietta, Georgia, United States

Southeastern Regional Medical Center, Inc. dba City of Hope Atlanta

Newnan, Georgia, United States

Pearlman Cancer Center

Valdosta, Georgia, United States

St Lukes Mountain States Tumor Institute

Boise, Idaho, United States

Kootenai Health

Coeur d'Alene, Idaho, United States

Northwestern Medicine

Chicago, Illinois, United States

Rush University Medical Center

Chicago, Illinois, United States

University of Illinois

Chicago, Illinois, United States

University of Chicago Medical Center

Chicago, Illinois, United States

NorthShore University Healthsystem

Evanston, Illinois, United States

Edward Hospital

Naperville, Illinois, United States

West Suburban Medical Center- River Forest

River Forest, Illinois, United States

Edward H. Kaplan MD & Associates - Hematology/Oncology of the North Shore

Skokie, Illinois, United States

Springfield Clinic LLP

Springfield, Illinois, United States

Carle Cancer Center

Urbana, Illinois, United States

Franciscan Health Indianapolis

Indianapolis, Indiana, United States

Investigative Clinical Research of Indiana, LLC

Indianapolis, Indiana, United States

IU Health Arnett Hospital

Lafayette, Indiana, United States

Franciscan Health Munster

Munster, Indiana, United States

Mercy Medical Center

Cedar Rapids, Iowa, United States

Mission Cancer & Blood - John Stoddard Cancer Center

Des Moines, Iowa, United States

University of Iowa Hospitals and Clinics

Iowa City, Iowa, United States

Cancer Center of Kansas

Wichita, Kansas, United States

University of Kentucky

Lexington, Kentucky, United States

Norton Healthcare, Inc.

Louisville, Kentucky, United States

Mercy Health

Paducah, Kentucky, United States

Mary Bird Perkins Cancer Center

Baton Rouge, Louisiana, United States

University Medical Center New Orleans

New Orleans, Louisiana, United States

New England Cancer Specialists

Scarborough, Maine, United States

Sinai Hospital of Baltimore, Inc.

Baltimore, Maryland, United States

St. Agnes Hospital

Baltimore, Maryland, United States

Johns Hopkins Medicine - The Sidney Kimmel Comprehensive Cancer Center

Baltimore, Maryland, United States

American Oncology Partners of Maryland, PA

Bethesda, Maryland, United States

James M Stockman Cancer Institute

Frederick, Maryland, United States

Greater Baltimore Medical Center

Towson, Maryland, United States

Massachusetts General Hospital

Boston, Massachusetts, United States

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

Dana Farber Cancer Institute

Boston, Massachusetts, United States

Dana-Farber Cancer Institute @Foxborough

Foxborough, Massachusetts, United States

Dana-Farber Cancer Institude at Merrimack Valley

Methuen, Massachusetts, United States

Dana Farber Cancer Institute @ Milford Regional Hospital

Milford, Massachusetts, United States

Dana-Farber/Brigham and Women's Cancer Center (DF/BWCC) in Clinical Affiliation with South Shore Hospital

South Weymouth, Massachusetts, United States

Baystate Medical Center Inc.

Springfield, Massachusetts, United States

University of Massachusetts Worcester

Worcester, Massachusetts, United States

Henry Ford Health System

Detroit, Michigan, United States

Cancer and Hematology Centers of Western Michigan

Grand Rapids, Michigan, United States

Ascension

Grosse Pointe Woods, Michigan, United States

William Beaumont Hospital

Royal Oak, Michigan, United States

Ascension Providence Hospital Southfield Cancer Center

Southfield, Michigan, United States

Trinity Health St. Joseph Mercy Ann Arbor

Ypsilanti, Michigan, United States

Minnesota Oncology Hematology, PA

Maplewood, Minnesota, United States

Virginia Piper Cancer Center (Allina Health)

Minneapolis, Minnesota, United States

University of Minnesota Medical Center, Fairview

Minneapolis, Minnesota, United States

Mayo Clinic Rochester

Rochester, Minnesota, United States

Metro Minnesota Community Oncology

Saint Louis Park, Minnesota, United States

Washington University School of Medicine

St Louis, Missouri, United States

Baptist Clinical Research Institute

St Louis, Missouri, United States

Mercy Hospital

St Louis, Missouri, United States

Mary Lanning Healthcare - Morrison Cancer Center

Hastings, Nebraska, United States

Oncology Hematology West - Methodist

Omaha, Nebraska, United States

Nebraska Methodist Hospital (change from Chi Health Bergan Mercy)

Omaha, Nebraska, United States

Comprehensive Cancer Centers of Nevada

Las Vegas, Nevada, United States

Cancer Care & Hematology Specialists

Reno, Nevada, United States

Regional Cancer Care Associates LLC

East Brunswick, New Jersey, United States

Hunterdon Medical Center

Flemington, New Jersey, United States

Summit Medical Group, P.A.

Florham Park, New Jersey, United States

Rutgers Health

New Brunswick, New Jersey, United States

Overlook Medical Center

Summit, New Jersey, United States

University of New Mexico

Albuquerque, New Mexico, United States

San Juan Oncology Associates

Farmington, New Mexico, United States

New York Oncology Hematology (NYOH)

Amsterdam, New York, United States

Roswell Park Cancer Institute

Buffalo, New York, United States

Hematology Oncology Associates of Central New York, PC

East Syracuse, New York, United States

Northwell Health

Lake Success, New York, United States

Laura and Isaac Perlmutter Cancer Canter

New York, New York, United States

Lipson Cancer Institute - Linden Oaks

Rochester, New York, United States

New York Cancer and Blood Specialists

Shirley, New York, United States

Stony Brook Medicine

Stony Brook, New York, United States

SUNY Upstate Medical University

Syracuse, New York, United States

Montefiore Medical Center

The Bronx, New York, United States

Clinical Research Alliance

Westbury, New York, United States

White Plains Hospital Physician Associates

White Plains, New York, United States

Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, United States

Duke Cancer Institute

Durham, North Carolina, United States

Cone Health Medical Group (Moses Cone Health System)

Greensboro, North Carolina, United States

East Carolina University Health Medical Center

Greenville, North Carolina, United States

FirstHealth Outpatient Cancer Center

Pinehurst, North Carolina, United States

UNC Rex Cancer Center

Raleigh, North Carolina, United States

UNC Nash Cancer Center

Rocky Mount, North Carolina, United States

Atrium Health Wake Forest Baptist

Winston-Salem, North Carolina, United States

Good Samaritan Hospital

Cincinnati, Ohio, United States

Oncology Hematology Care, Inc.

Cincinnati, Ohio, United States

Ohio State University CRS

Columbus, Ohio, United States

Ohio Health Research Institute

Columbus, Ohio, United States

Columbus NCORP

Columbus, Ohio, United States

Anita Stewart Oncology Center

Columbus, Ohio, United States

Toledo Clinic Cancer Center

Toledo, Ohio, United States

University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, United States

St. Charles Health System, Inc. DBA St. Charles Medical Center

Bend, Oregon, United States

Samaritan Hospital

Corvallis, Oregon, United States

Willamette Valley Cancer Institute and Research Center

Eugene, Oregon, United States

Asante Rogue Regional Medical Center

Medford, Oregon, United States

Providence Cancer Institute - Oncology Clinical Trials

Portland, Oregon, United States

Oregon Health & Science University

Portland, Oregon, United States

Saint Luke's University Hospital

Bethlehem, Pennsylvania, United States

Lancaster General Health

Lancaster, Pennsylvania, United States

University of Pennsylvania Abramson Cancer Center

Philadelphia, Pennsylvania, United States

UPMC Magee-Womens Hospital

Pittsburgh, Pennsylvania, United States

Guthrie Clinical Research

Sayre, Pennsylvania, United States

Reading Hospital and Medical Center

West Reading, Pennsylvania, United States

Lankenau Medical Center

Wynnewood, Pennsylvania, United States

Cancer Care Associates of York

York, Pennsylvania, United States

Providence Health

Providence, Rhode Island, United States

Medical University of South Carolina

Charleston, South Carolina, United States

Spartanburg Medical Center

Spartanburg, South Carolina, United States

Monument Health Cancer Care Institute

Rapid City, South Dakota, United States

Avera Cancer Institute

Sioux Falls, South Dakota, United States

Ballad Health Cancer Care - Kingsport

Kingsport, Tennessee, United States

Center for Biomedical Research, LLC

Knoxville, Tennessee, United States

University of Tennessee

Knoxville, Tennessee, United States

Hendrick Health System

Abilene, Texas, United States

Texas Oncology

Austin, Texas, United States

Texas Oncology

El Paso, Texas, United States

MD Anderson Cancer Center

Houston, Texas, United States

Joe Arrington Cancer Research and Treatment Center

Lubbock, Texas, United States

Texas Oncology

San Antonio, Texas, United States

Huntsman Cancer Institute

Salt Lake City, Utah, United States

University of Virginia

Charlottesville, Virginia, United States

Inova Fairfax Hospital

Fairfax, Virginia, United States

Bon Secours Cancer Institute at St. Francis

Midlothian, Virginia, United States

Virginia Commonwealth University Medical Center

Richmond, Virginia, United States

Oncology and Hematology Associates of Southwest Virginia, Inc

Wytheville, Virginia, United States

Providence Regional Cancer System

Lacey, Washington, United States

MultiCare Regional Cancer Center - Tacoma

Puyallup, Washington, United States

Northwest Medical Specialties, PLLC

Puyallup, Washington, United States

University of Washington

Renton, Washington, United States

Medical Oncology Associates

Spokane, Washington, United States

West Virginia University Hospital

Morgantown, West Virginia, United States

ThedaCare Regional Cancer Center

Appleton, Wisconsin, United States

Ascension St. Francis Reiman Cancer Center

Franklin, Wisconsin, United States

HSHS Saint Mary's Hospital Medical Center - Green Bay

Green Bay, Wisconsin, United States

University of Wisconsin

Madison, Wisconsin, United States

Macarthur Cancer Therapy Centre, Campbelltown Hospital

Campbelltown, New South Wales, Australia

Kinghorn Cancer Centre

Darlinghurst, New South Wales, Australia

Lake Macquarie Private Hospital

Gateshead, New South Wales, Australia

Port Macquarie Base Hospital

Port Macquarie, New South Wales, Australia

Cairns Hospital

Cairns, Queensland, Australia

Princess Alexandra Hospital

Woolloongabba, Queensland, Australia

Cancer Research SA

Adelaide, South Australia, Australia

Bendigo Health

Bendigo, Victoria, Australia

Monash Medical Centre

Clayton, Victoria, Australia

Fiona Stanley Hospital

Murdoch, Western Australia, Australia

Chirec Delta Hospital

Brussels, Belgium

UZ Leuven

Leuven, Belgium

Clinique CHC MontLégia

Liège, Belgium

AZ Delta vzw

Roeselare, Belgium

Ziekenhuls aan de Stroom vzw (ZAS vzw), ZAS Augustinus

Wilrijk, Belgium

St. de Habitações Individuais Sul QI 15 - Lago Sul, Brasília - DF, Brasil

Brasília, Brazil

Rua Myltho Anselmo da Silva, 870 - Mercês, Curitiba - PR, CEP 80510-130

Curitiba, Brazil

Oncosite

Ijuí, Brazil

R. Aderbal Ramos da Silva, 148 - Centro, Itajaí - SC, 88300-000, Brasil

Itajaí, Brazil

Av. Miguel Castro, 1355, Nossa Senhora de Nazaré, Natal/RN

Natal, Brazil

Rua Professor Annes Dias, 295 - Centro Histórico, Porto Alegre - RS, , Brasil

Porto Alegre, Brazil

Av. Soledad, 569, sala 1103, Três Figueiras, CEP 90470-340

Porto Alegre, Brazil

Av. Ipiranga 6690

Porto Alegre, Brazil

Av. Milton Santos, 123 - Ondina, Salvador - BA, , Brasil

Salvador, Brazil

AMO Clinic - Rio Vermelho

Salvador, Brazil

Av. Brigadeiro Luís Antônio 733, loja 8

São Paulo, Brazil

Martiiano de Carvalho 965

São Paulo, Brazil

CIPE Centro Internacional de Pesquisa; A.C. Camargo Cancer Center

São Paulo, Brazil

Rua Gardênia, 710, Edifício Prime, 4º andar, Bairro Jóquei, Teresina - PI, CEP 60449-200

Teresina, Brazil

CHU Amiens Picardie

Amiens, France

Pôle Santé Léonard De Vinci - ROC37

Chambray-lès-Tours, France

Clinique Victor Hugo

Le Mans, France

chu de Limoges

Limoges, France

Institut de Cancérologie de l'Ouest (ICO) - St Herblain

Loire Atlantique, France

Hôpital Privé Jean Mermoz

Lyon, France

Centre D'Oncologie de Gentilly

Nancy, France

L'Hôpital Privé du Confluent

Nantes, France

CHU de Nimes

Nîmes, France

Hopital Privé des Côtes d'Armor - Centre CARIO-HPCA

Plérin, France

CHU de Poitiers, 2 Rue de la Milétrie

Poitiers, France

Centre Eugène Marquis

Rennes, France

Oncopole Claudius Regaud - IUCT-O

Toulouse, France

Hämatologie-Onkologie im Zentrum MVZ GmbH

Augsburg, Germany

Schwanebecker Chaussee 50

Berlin, Germany

Möllendorffstr. 52, 10367 Berlin 2. Behandlungsstandort: Markt 2-3, 13597 Berlin

Berlin, Germany

Teutoburger Str. 60

Bielefeld, Germany

Josef-Albers-Str.70

Bottrop, Germany

Studien GbR Braunschweig

Braunschweig, Germany

St.-Juergen-Str. 1

Bremen, Germany

Hämato-Onkologische Praxis im Medicum

Bremen, Germany

St. Elisabeth Krankenhaus GmbH

Cologne, Germany

St. Johannes Hospital

Dortmund, Germany

Fetscherstraße ,74

Dresden, Germany

Kostara Gyn. Oncology Clinic Research UG

Düsseldorf, Germany

Universitätsstraße, 21-23

Erlangen, Germany

Henricistraße 92, 45136 Essen, Germany

Essen, Germany

Klinikum Esslingen

Esslingen am Neckar, Germany

Gotenstraße 6-8

Frankfurt am Main, Germany

Hugstetter Str. 55

Freiburg im Breisgau, Germany

Munckelstrasse 27

Gelsenkirchen, Germany

MVZ II der Niels Stensen Kliniken

Georgsmarienhütte, Germany

Straße des Friedens 122

Gera, Germany

Hohe Weide 17b

Hamburg, Germany

Moorkamp 2-6

Hamburg, Germany

Am Klinikum 1

Jena, Germany

Edgar-von-Gierke-Straße 2

Karlsruhe, Germany

Elisabeth Krankenhaus Brustzentrum

Kassel, Germany

Arnold-Heller-Str. 3 Haus C

Kiel, Germany

InVO - Institut für Versorgungsforschung in der Onkologie GbR / Praxis für Hämatologie und Onkologie

Koblenz, Germany

Lutherplatz 40

Krefeld, Germany

Fachärztezentrum Langen

Langen, Germany

Liebigstraße 20

Leipzig, Germany

Biedermannstrasse 84

Leipzig, Germany

Universitätsklinikum Mannheim

Mannheim, Germany

Taxisstrasse 3

Munich, Germany

Bei der Marienkirche 6

Mühlhausen, Germany

Albert-Schweitzer-Campus 1, Building A1,

Münster, Germany

Starkenburgring 66, 63069 Offenbach

Offenbach, Germany

Rahel-Straus-Straße 10

Oldenburg, Germany

Husenerstr. 81

Paderborn, Germany

Charlottenstraße 72

Potsdam, Germany

Elisabethenstr. 19, 88212 Ravensburg

Ravensburg, Germany

Südring 81

Rostock, Germany

Wismarsche Strasse 393-397

Schwerin, Germany

Harsefelderstraße 8

Stade, Germany

Böheimstr. 37

Stuttgart, Germany

Schierghoferstrasse 1

Traunstrein, Germany

Calwerstrasse 7

Tübingen, Germany

Prittwitzstr. 43

Ulm, Germany

Beethovenstrasse 20

Wiesbaden, Germany

Marienplatz 2

Witten, Germany

Klinikum Worms Frauenklinik

Worms, Germany

Helios University Hospital University Witten/Herdecke

Wuppertal, Germany

Mater Misericordiae University Hospital

Dublin, Ireland

St James's Hospital

Dublin, Ireland

Beaumont Hospital

Dublin, Ireland

University Hospital Limerick

Limerick, Ireland

Cork University Hospital

Wilton, Ireland

IRCCS Istituto Tumori "Giovanni Paolo II"

Bari, Italy

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Italy

Azienda Ospedaliera Universitaria Careggi

Florence, Italy

Istituto Romagnolo Per Lo Studio Dei Tumori (IRST) 'Dino Amadori? IRCCS

Meldola, Italy

Humanitas Istituto Clinico Catanese

Misterbianco, Italy

AOU Modena

Modena, Italy

IRCCS Fondazione G. Pascale

Naples, Italy

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Roma, Italy

Fondazione Policlinico Universitario Campus Bio-Medico di Roma

Rome, Italy

ASST Papa Giovanni XXIII

Rozzano, Italy

AOU Città della Salute e della Scienza di Torino

Torino, Italy

Ospedale Santa Chiara

Trento, Italy

Soonchunhyang University Cheonan Hospital

Chungcheongnam-do, South Korea

Kyungpook National University Chilgok Hospital

Daegu, South Korea

Seoul National University Bundang Hospital

Gyeonggi-do, South Korea

Severance Hospital

Seodaemun-gu, South Korea

Korea University Anam Hospital

Seoul, South Korea

Asan Medical Center

Seoul, South Korea

Gangnam Severance Hospital

Seoul, South Korea

Seoul National University Hospital

Seoul, South Korea

Samsung Medical Center

Seoul, South Korea

The Catholic University of Korea, Seoul St. Mary's Hospital

Seoul, South Korea

Medical Oncology Unit. A Coruña University Hospital

A Coruña, Spain

ICO Badalona - Hospital Germans Trias I Pujol

Badalona, Spain

Hospital Universitary of Cruces

Barakaldo, Spain

Hospital Clinic de Barcelona

Barcelona, Spain

Hospital del Mar

Barcelona, Spain

Hospital de la Santa Creu i Sant Pau

Barcelona, Spain

Consorcio Hospitalario Provincial de Castellón

Castellon, Spain

Hospital Universitario San Pedro de Alcántara

Cáceres, Spain

Hospital Reina Sofia

Córdoba, Spain

Hospital Donostia

Donostia / San Sebastian, Spain

Hospital General Universitario De Elche

Elche, Spain

Hospital Universitario de Fuenlabrada

Fuenlabrada, Spain

Hospital Galdakao

Galdakao, Spain

Hospital Universitario Virgen de las Nieves

Granada, Spain

Hospital Universitario Clínico San Cecilio

Granada, Spain

Hospital Universitario de Jaen

Jaén, Spain

H. León

León, Spain

Hospital Arnau de Vilanova

Lleida, Spain

Hospital Beata María Ana

Madrid, Spain

Hospital General Universitario Gregorio Maranon

Madrid, Spain

Althaia Xarxa Assistencial de Manresa

Manresa, Spain

Hospital Universitario Virgen de la Victoria

Málaga, Spain

Hosp. Mat-Inf. Carlos Haya

Málaga, Spain

Hospital General Univers

Murcia, Spain

Hospital Universitario Morales Meseguer

Murcia, Spain

Clínica Universidad de Navarra - Madrid

Pamplona, Spain

Hospital Universitari Sant Joan de Reus

Reus, Spain

Hospital Parc Tauli

Sabadell, Spain

Hospital Universitario de Canarias

San Cristóbal de La Laguna, Spain

HU Marqués de Valdecilla

Santander, Spain

Hospital Universitario Virgen Macarena

Seville, Spain

Hospital Quironsalud Sagrado Corazón

Seville, Spain

Hospital de Toledo

Toledo, Spain

Hospital Clínico Universitario de Valencia

Valencia, Spain

Hospital Clínico Universitario de Valencia

Valencia, Spain

Hospital Clinico Universitario de Valladolid

Valladolid, Spain

Isabel la Catolica nº 1-3

Zaragoza, Spain

Hull University Teaching Hospitals NHS Trust

Cottingham, United Kingdom

The Clatterbridge Cancer Centre NHS Foundation Trust

Liverpool, United Kingdom

Barts Health NHS Trust

London, United Kingdom

Guy's Hospital

London, United Kingdom

Royal Marsden Hospital

London, United Kingdom

The Christie NHS Foundation Trust

Manchester, United Kingdom

East and North Hertfordshire NHS Trust

Northwood, United Kingdom

Taunton and Somerset NHS Foundation Trust

Taunton, United Kingdom

York Teaching Hospital NHS Foundation Trust

York, United Kingdom

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NCT05633654

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