RecruitingNCT05634200

Utility of Bronchoscopy in Patients With Haemoptysis and Negative Chest CT Scan (ULYSSES)

Utility of Bronchoscopy in Patients With Haemoptysis and Negative Chest CT Scan: an Observational, Prospective, Multicentre Study (ULYSSES)

Sponsor

University of Milan

Enrollment

150 participants

Start Date

Oct 1, 2022

Study Type

OBSERVATIONAL

Conditions

Hemoptysis

Summary

Conflicting evidence exist in the literature on the utility of bronchoscopy in patients with haemoptysis and negative/non-diagnostic chest CT scan. The primary aim of this prospective, observational, multicenter study is to evaluate the utility of bronchoscopy in patients with haemoptysis and negative/non-diagnostic CT scans. Secondary aims are related to the utility of bronchoscopy to detect occult malignancies, the source of the bleeding and the clinical features of the cohort

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study examines whether bronchoscopy (a camera procedure to look inside the airways) is useful for finding the cause of coughing up blood (haemoptysis) in patients whose chest CT scan came back normal or inconclusive. It aims to determine if bronchoscopy adds value when imaging doesn't explain the bleeding. **You may be eligible if...** - You are 18 years or older - You have been coughing up blood (haemoptysis) and the cause is unknown - Your chest CT scan was normal or did not give a clear diagnosis **You may NOT be eligible if...** - Your CT scan already identified a known cause for the bleeding - You have known bleeding lesions in your airways - You refused to sign the consent form Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBronchoscopy

During bronchoscopy endobronchial biopsy, transbronchial biopsy, transbronchial needle aspiration, bronchial washing, bronchoalveolar lavage, EBUS-TBNA and EUS-B-FNA may be performed

Locations(14)

- Respiratory Unit, ASST Papa Giovanni XVIII

Bergamo, Italy

- Interventional Pulmonology Unit, Policlinico S. Orsola-Malpighi

Bologna, Italy

Department of Pulmonary and Critical Care Medicine, Sant'Anna Hospital

Como, Italy

Respiratory Unit, ASST Lodi

Lodi, Italy

Respiratory Unit, ASST Santi Paolo e Carlo

Milan, Italy

- Respiratory Unit, Sacco Hospital, ASST Fatebenefratelli-Sacco

Milan, Italy

Respiratory Unit, San Gerardo Hospital, ASST Monza

Monza, Italy

Interventional Pulmonology Unit, Dept of Pulmonology, Oncology and Hematology, Cardarelli Hospital

Naples, Italy

- Respiratory Unit, IRCCS Foundation Policlinico San Matteo

Pavia, Italy

Pulmonology Unit, Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia

Reggio Emilia, Italy

- Interventional Pulmonology Unit, Policlinico Agostino Gemelli

Roma, Italy

- Respiratory Unit, A.O.U. Città della Salute e della Scienza di Torino

Torino, Italy

Department of Pulmonology, University Hospital of Udine (ASUFC)

Udine, Italy

Interventional Pulmonology Unit, Respiratory Department, University Hospital Santa Creu i Sant Pau

Barcelona, Spain

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