Outpatient Rehabilitation Intervention for Young Children With SMA
Twice Weekly Outpatient Rehabilitation Intervention for Young Children With Spinal Muscular Atrophy Treated With Genetic Based Therapies: A Feasibility Study
Holland Bloorview Kids Rehabilitation Hospital
10 participants
Jan 1, 2022
INTERVENTIONAL
Conditions
Summary
An outpatient rehabilitation program for children (6 months to less than 6 years old) with Spinal Muscular Atrophy (SMA) treated with genetic based therapies is being studied. Participants will participate in a 12-week therapy program where they receive 45 minutes each of occupational therapy and physical therapy each week. Home exercises will also be prescribed to be completed 5 days per week. At the end of the therapy program, there will be a 12-week period of no therapy where only home exercises will be completed. Assessments and program evaluation will occur at the beginning (Week 0) and end of the rehabilitation program (Week 24), then at the end of the no therapy block (week 24).
Eligibility
Inclusion Criteria8
- SMA (Type I, II or III) diagnosis;
- Receives genetic based therapy;
- Aged 6 months to less than 6 years old;
- Able to participate in weekly therapy at Holland Bloorview (i.e., can attend in-person sessions);
- Able to bring appropriate respiratory equipment to weekly therapy sessions, if required;
- Substitute decision makers (SDMs) must be able to speak and read English;
- Child participant must be able to understand/follow directions in English, as age appropriate;
- SDMs must consent to participate on behalf of their child.
Exclusion Criteria2
- Live outside of Ontario;
- Tracheostomy or use of daytime ventilation (excluding ventilation used during naps).
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Interventions
12-week treatment intervention \& home exercised, then 12-week non-intervention period, follow-up visit at end of non-intervention period.
Locations(1)
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NCT05638750