RecruitingNCT05640102

Observational Study Evaluating the Efficacy and Safety of Zanubrutinib in Participants With Waldenström Macroglobulinemia

A Phase 4, Observational Study Evaluating the Efficacy and Safety of the Bruton Tyrosine Kinase (BTK) Inhibitor Zanubrutinib in Patients With Waldenström Macroglobulinemia


Sponsor

BeiGene

Enrollment

111 participants

Start Date

Mar 3, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This is a hybrid (retrospective and prospective) non-interventional registry study to further describe the clinical profile of zanubrutinib in Waldenström macroglobulinemia (WM) participants with and without specific mutations and from racial and ethnic minority groups. Data collected from this registry study will be used to better understand the clinical benefit and safety of zanubrutinib for the treatment of participants in these populations.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Zanubrutinib for people with waldenstrom macroglobulinemia. The study is currently recruiting participants at 8 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGZanubrutinib

Dosing and treatment duration are at the discretion of the prescribing physician and in accordance with local labeling


Locations(8)

Clearview Cancer Institute

Huntsville, Alabama, United States

South Alabama Medical Science Foundation Mitchell Cancer Institute

Mobile, Alabama, United States

City of Hope National Medical Center

Duarte, California, United States

Los Angeles Cancer Network (Lacn)

Glendale, California, United States

Eisenhower Medical Center, Lucy Curci Cancer Center

Rancho Mirage, California, United States

Hattiesburg Hematology and Oncology Clinic

Hattiesburg, Mississippi, United States

Comprehensive Cancer Centers of Nevada

Las Vegas, Nevada, United States

Pan American Oncology Trials, Llc

Rio Piedras, Puerto Rico

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NCT05640102


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