A Novel Intervention for Patients With Cancer
A Novel Intervention for Avoidance-Related Opioid Misuse in Patients With Cancer
Dana-Farber Cancer Institute
40 participants
Mar 1, 2023
INTERVENTIONAL
Conditions
Summary
This research study is being done to develop an intervention for psychological symptoms that patients diagnosed with cancer may experience. Psychological symptoms may include thoughts, feelings, emotions, and memories The names of the study intervention and research activities involved in this study are/is: * Acceptance \& Commitment Therapy (ACT) for Cancer (involving 6 sessions with a licensed clinical psychologist) * Questionnaires * Post-study interview Consistent with the NIH Stage Model for Behavioral Intervention Development, the investigators have adapted an existing, empirically-validated intervention, Acceptance and Commitment Therapy (ACT), to address substance use disorder risk during cancer care. The core components of ACT are particularly well-suited to address the psychological processes underlying opioid misuse in individuals treated for cancer pain. The overarching aim is to assess the feasibility and acceptability of the intervention by conducting a randomized pilot trial of the revised intervention ("ACTION") for cancer patients on opioid therapy, and at risk for SUD.
Eligibility
Inclusion Criteria5
- at least 18 years old
- have an estimated survival time of at least 6 months (as estimated by palliative care provider)
- score at least 4 on the Opioid Risk Tool (ORT)
- have been diagnosed with any cancer, including hematologic malignancies
- performance status criterion of 0, 1, or 2 \[ with 0 indicating that the patient is asymptomatic, 1 that the patient is symptomatic but fully ambulatory, and 2 that the patient is symptomatic and in bed <50% of the day\]
Exclusion Criteria4
- Patients with a score at least 3 to ensure that all enrolled patients are able to participate in the intervention, complete assessments, ensure that no patients who are too sick to participate are enrolled; this will enhance the rigor of the study)
- currently be on opioid therapy
- not meet criteria for current substance use disorder
- assessed by the Diagnostic \& Statistical Manual of mental disorders; DSM-5 or be receiving substance use disorder treatment; and speak and comprehend English sufficiently to be able to participate in psychotherapy.
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Interventions
Six-session, skills-based behavioral intervention targeting risk factors for opioid use disorder in the context of cancer
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05643027