Biologics for Stricturing Crohn's Diseases

This study is investigating the use of biologic drugs (a type of targeted anti-inflammatory treatment) for people with Crohn's disease who have developed narrowing of the intestine (called stricturing Crohn's disease), to see if biologics can manage the condition and avoid surgery. **You may be eligible if...** - You have stricturing (narrowing) Crohn's disease - Surgery has not been recommended for your condition - You may also have asymptomatic (non-troublesome) penetrating disease (tunneling complications that are not causing symptoms) - You have given written consent to participate **You may NOT be eligible if...** - You have been recommended for surgery - You have symptomatic penetrating disease (complications causing significant symptoms) - You have a contraindication to biologic medications - You are already enrolled in or planning to join another clinical trial Talk to your doctor to see if this trial is right for you.