Neonatal Brain Ultrasound With CEUS and Elastography
Contrast Enhanced Ultrasound and Elastography of the Neonatal Brain
Turku University Hospital
100 participants
Jan 1, 2024
INTERVENTIONAL
Conditions
Summary
The aim of our study is to investigate changes of brain perfusion and elasticity in neonates during the time that a neonate is adapting to live outside the womb and during diseases that are suspected to affect neonatal brain perfusion. We use contrast enhanced ultrasound (sulphur hexafluoride) and ultrasound-assisted elastography to evaluate the state of brain perfusion. We will study neonates recruited from the Neonatal Units of Turku University Hospital.
Eligibility
Inclusion Criteria1
- Babies less than 7 months treated at the neonatal units of Turku University hospital
Exclusion Criteria8
- Pre-known genetic disease
- Difficult congenital malformations that need surgical treatment
- Central nervous system tumors
- Weight less than 2,5 kg during examination
- Medical history of SonoVue hypersensitivity
- Uncontrolled systemic hypertension
- Systolic pulmonary artery pressure \> 90 mmHg
- Unstable cardiovascular state
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Interventions
To study brain perfusion with brain ultrasound, contrast enhanced ultrasound of the brain and ultrasound-guided shear-wave elastography
To evaluate the differences in brain perfusion studied by CEUS, comparing different patient groups and babies with no suspected brain pathology
Locations(1)
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NCT05648812