RecruitingNCT05654025

Follow up Study on Visual Prognosis and Complications of Ectopia Lentis Lens


Sponsor

Zhongshan Ophthalmic Center, Sun Yat-sen University

Enrollment

604 participants

Start Date

Dec 5, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

This is a single-centre, observational cohort study with the following objectives: Firstly, the investigators aim to evaluate the vision-related quality of life and mental health status in congenital ectopia lentis patients. Secondly, the investigators target to investigate the correlations between genotype and clinical phenotype in patients of congenital ectopia lentis. Thirdly, to explore the metabolic profiles in the aqueous humor (AH) of patients with congenital ectopia lentis. Lastly, this study aims to explore the longitudinal changes of ocular biological parameters and complications in patients with postoperative congenital ectopia lens in the Chinese population.


Eligibility

Min Age: 3 Years

Inclusion Criteria2

  • Diagnosed with congenital lens dislocation and age ≥ 3 years old.
  • Agree to participate in this study with written informed consent from patients or legal guardians.

Exclusion Criteria3

  • History of ophthalmic trauma or other ophthalmic surgeries.
  • Combined with other ophthalmic diseases such as primary glaucoma, uveitis and corneal disease.
  • Patients who could not cooperate in the examinations.

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Locations(1)

Guangdong Provincial Clinical Research Center for Ocular Diseases, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science

Guangzhou, Guangdong, China

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NCT05654025


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