RecruitingNot ApplicableNCT05658081

Comparison of Two Stapled Antimesenteric Anastomosis for CD: a Randomized Control Trial Study

Stapled Antimesenteric Functional End-to-end Anastomosis (Kono-S) Versus Stapled Antimesenteric Isoperistaltic Side-to-side Anastomosis for the Postoperative Recurrence of Crohn's Disease: a Randomized Control Trial Study


Sponsor

Jinling Hospital, China

Enrollment

236 participants

Start Date

Dec 8, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The postoperative recurrence of Crohn's diseases (CD) remains high. Stapled anti-mesenteric functional end-to-end anastomosis was safe for CD patients. Its impact on the postoperative recurrence of CD was unknown. Whether it is superior than the conventional anastomosis (stapled antimesenteric isoperistaltic side-to-side anastomosis) needs explored. The trial aims to compare the different impacts of the two antimesenteric anastomosis configurations on the anastomotic recurrence following bowel resection.


Eligibility

Min Age: 16 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This randomized controlled study compares two surgical techniques for reconnecting the bowel after removing a diseased section of intestine in people with Crohn's disease. Both techniques are types of stapled anastomosis (bowel reconnection), but they differ in design. The study aims to find out which method better prevents Crohn's disease from recurring at the reconnection site. **You may be eligible if...** - You have Crohn's disease and need surgery to remove a section of bowel - Your surgery involves reconnecting the small intestine to the large intestine at the ileocolic junction - You are able to provide written consent **You may NOT be eligible if...** - Your surgery requires creating an ostomy (stoma bag) rather than reconnecting the bowel - Your reconnection will be between two segments of small bowel only (not involving the colon) - You are already enrolled in another clinical trial Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREKono-S group

patients in this arm will receive stapled Kono-S anastomosis after bowel resection

PROCEDURESide-to-side group

patients in this arm will receive stapled antimesenteric isoperistaltic side-to-side anastomosis after bowel resection


Locations(1)

Department of General Surgery, Jinling hosptal,Medical School of Nanjing University

Nanjing, Jiangsu, China

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NCT05658081


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