RecruitingPhase 4NCT05669534

Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

Sponsor

University of Connecticut

Enrollment

256 participants

Start Date

Mar 1, 2023

Study Type

INTERVENTIONAL

Conditions

Opioid-use Disorder HIV

Summary

The investigators will conduct an optimization trial among N=256 PWID newly started on medication for opioid use disorder and Pre-Exposure Prophylaxis (PrEP) to assess the performance of four intervention components (Attention, Executive Functioning, Memory, and Information Processing) aimed at enhancing the ability of PWID on MOUD to process and utilize HIV prevention content, leading to improvements in HIV prevention information, motivation, behavioral skills, and behaviors (IMB).

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether a specialized support program can improve adherence to PrEP (a daily pill that prevents HIV) in people who inject drugs and have mild cognitive difficulties. The program combines mobile technology with behavioral support to help participants stay on track with their HIV prevention medication. **You may be eligible if...** - You are 18 or older - You have recently started PrEP (within the past week) and are HIV-negative - You are on medication for opioid use disorder (such as methadone or buprenorphine) - You have mild cognitive difficulties based on a memory screening test - You have engaged in unsafe injection drug use or unprotected sex in the past 3 months - You have a cell phone **You may NOT be eligible if...** - You are HIV-positive - You have severe cognitive impairment - You are not currently on medication-assisted treatment for opioid use - You started PrEP more than a week ago Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALcommunity-friendly health recovery program

Participants will receive 4 weekly 45 minute sessions HIV prevention sessions.

DRUGPre-Exposure Prophylaxis and Post-Exposure Prophylaxis

Participants will be prescribed Pre-exposure prophylaxis (PrEP) is a biomedical intervention.

Locations(1)

APT Foundation

New Haven, Connecticut, United States

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NCT05669534

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