RecruitingPhase 4NCT07199335

Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs

A Multi-Center Assessment of an Intervention to Provide Long-Acting Cabotegravir Injectable Pre-Exposure Prophylaxis to People Who Inject Drugs


Sponsor

Massachusetts General Hospital

Enrollment

100 participants

Start Date

Feb 24, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to determine the feasibility and impact of delivering long-acting injectable cabotegravir HIV pre-exposure prophylaxis and suite of support services to adults who inject non-prescription drugs who are risk for HIV through known sexual risk.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a long-acting injectable form of PrEP (pre-exposure prophylaxis) called cabotegravir for people who inject drugs and are at risk of HIV. Instead of a daily pill, cabotegravir is given as an injection every 2 months to help prevent HIV infection. **You may be eligible if...** - You are 18 or older - You have injected non-prescribed drugs in the past 6 months - You tested HIV-negative at enrollment - You have not previously used cabotegravir - Your doctor thinks injectable PrEP is appropriate for you **You may NOT be eligible if...** - You are currently pregnant or breastfeeding - You have already been diagnosed with HIV - You prefer to continue daily oral PrEP pills rather than switching to injections Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGAPRETUDE (cabotegravir)

All participants will be prescribed APRETUDE based on APRETUDE's FDA approved indication, which is sexual risk of HIV transmission.


Locations(2)

Massachusetts General Hospital

Boston, Massachusetts, United States

Fenway Health

Boston, Massachusetts, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07199335


Related Trials