International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery

This international study monitors brain oxygen levels and electrical activity in newborns undergoing major surgery for congenital conditions — including diaphragmatic hernia, gastroschisis, bowel problems, and spinal defects. Surgery in newborns carries risks of brain injury. By attaching non-invasive brain monitors during surgery, researchers aim to detect early signs of brain stress and find ways to protect newborn brains during these procedures. **You may be eligible if...** - Your baby is 60 weeks postmenstrual age or younger at the time of surgery - Your baby is undergoing neonatal surgery for a listed congenital condition (including diaphragmatic hernia, gastroschisis, intestinal atresia, esophageal fistula, or spina bifida) - Parents or guardians have given permission **You may NOT be eligible if...** - Your baby has hydrocephalus limiting the frontal-parietal brain area, severe brain bleeding (grade 3 or 4), brain malformation, or cerebral infarction in the area where monitoring sensors are placed **Talk to your neonatologist or neonatal surgeon if** your newborn is scheduled for surgery and you want to know about brain monitoring research during the procedure.