RecruitingNCT05677880

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

Unraveling the Early Phases of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL)

Sponsor

University of Wisconsin, Madison

Enrollment

660 participants

Start Date

Jun 3, 2022

Study Type

OBSERVATIONAL

Conditions

Cadasil

Summary

This is an observational study to better understand the risk factors and progression of CADASIL, a leading cause of vascular cognitive impairment and dementia (VCID). 575 participants will be enrolled and can expect to be on study for up to 5 years.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Study Procedures for people with cadasil. The study is currently recruiting participants at 12 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERStudy Procedures

Participants will experience * Neurocognitive Tests and Self-Report Measures * Clinical Interviews * Neurological Exam * MRI screening at baseline, 18 months, 36 months * Fasted Blood draw

Locations(12)

University of California

Los Angeles, California, United States

University of California

San Francisco, California, United States

University of Colorado

Denver, Colorado, United States

Georgia State University Research Foundation

Atlanta, Georgia, United States

Loyola University

Chicago, Illinois, United States

Columbia University

New York, New York, United States

Oregon Health & Science University

Portland, Oregon, United States

Brown University

Providence, Rhode Island, United States

University of Texas Health Science Center

Houston, Texas, United States

University of Texas

San Antonio, Texas, United States

University of Utah

Salt Lake City, Utah, United States

University of Washington

Seattle, Washington, United States

View Full Details on ClinicalTrials.gov

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NCT05677880

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