RecruitingNot ApplicableNCT05683106

Effects of Customized Silicone Digital Orthoses in People With Diabetic Neuropathy

Effects of the Use of Customized Silicone Digital Orthoses on Pre-ulcerative Lesions and Plantar Pressure During Walking in People With Diabetic Neuropathy: a Randomized Controlled Clinical Trial


Sponsor

University of Sao Paulo General Hospital

Enrollment

60 participants

Start Date

Sep 6, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The present study aims to evaluate the efficacy and safety of the use of customized silicone digital orthoses for six months in the distribution of plantar pressure, in the reduction of pre-ulcerative lesions and plantar ulcers in the forefoot, foot deformities, quality of life and foot health and functionality in people with diabetes and neuropathy with risk category 2 and 3 for ulcers, according to the International Working Group on Diabetic Foot.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria3

  • Diagnosed type 1 or 2 diabetes, with diabetic peripheral neuropathy confirmed by loss of sensitivity measured by 10 g Semmes-Weinstein monofilament or 128Hz tuning fork and by the fuzzy score (www.usp.br/labimph/fuzzy);
  • Presence of 1 or more deformities at the forefoot region (claw toes, hammer toes, mallet toes, overlapping toes, hallux valgus, prominence of the metatarsal heads or reduction/displacement of the fat pad);
  • Ability to walk independently with or without the aid of a walking device;

Exclusion Criteria8

  • Presence of other diagnosed neurological diseases;
  • Presence of dementia or inability to give consistent information;
  • Presence of major vascular complications;
  • Receiving any physiotherapy intervention;
  • Major vascular complications (ischemia)
  • Presence of an active ulcer at the time of baseline assessment;
  • Major amputations;
  • Minor amputations, except toes.

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Interventions

DEVICECustom silicone digital orthosis (CSDO)

Custom silicone digital orthosis (CSDO) will be made under mold to provide realignment of toes, protection or replacement of a segment that was amputated.They will be indicated for corrections of rigid/fixed or flexible toes deformities.CSDO will be constructed using different types of silicone and different hardness considering whether the deformities are rigid or flexible and,when necessary,these components of the orthoses will be merged.Intervention participants will be asked to clean the CSDO and interdigital spaces with soap and water;adequate drying of the fingers and interdigital region;always wear the CSDO with appropriate footwear and socks;keep monitoring the integrity of the CSDO and always communicate any identification of changes in the feet or CSDO.Adverse effects will be evaluated, such as:possible skin irritation; discomfort or pain;contractures;trauma due to friction.Adherence will be verified every 3 months and via telephone contact,monthly.


Locations(1)

Stay Care Clinica

São Paulo, São Paulo, Brazil

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NCT05683106


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