Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords
Eye & ENT Hospital of Fudan University
100 participants
May 5, 2023
INTERVENTIONAL
Conditions
Summary
To provide a novel therapy idea and method to solve the clinical problem of postoperative adhesion of bilateral vocal cords, patients enrolled in this study will be applied with curcumin on both wound sites of bilateral vocal cords after the surgery on the bilateral vocal cord endoscopically.
Eligibility
Inclusion Criteria2
- Patients with bilateral vocal cord diseases who are going to undergo resection of bilateral vocal cord lesions endoscopically.
- Patients with bilateral vocal cord adhesion who are going to undergo incision of bilateral vocal cord adhesion endoscopically.
Exclusion Criteria6
- Patients with other laryngeal diseases.
- Patients with cardiac and pulmonary insufficiency.
- Patients unable to cooperate with the follow-up on time after surgery.
- Patients who refuse to sign the informed consent after notification.
- Patients who have a severe allergic disease or allergic history to a variety of drugs.
- Other circumstances that are not appropriate to be included in the clinical trial.
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Interventions
Curcumin was applied to both wound sites of bilateral vocal cords. After evenly applied, gently massage the applied site for 3-5 minutes until the drug was fully absorbed.
Mitomycin-C was applied to both wound sites of bilateral vocal cords. After evenly applied, gently massage the applied site for 3-5 minutes until the drug was fully absorbed.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05688488