RecruitingNCT05697861

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Long-Term Follow-Up of Subjects Treated With NTLA-2001


Sponsor

Intellia Therapeutics

Enrollment

72 participants

Start Date

Jul 10, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This is a follow-up study of subjects who received NTLA-2001 in a previous clinical trial as an observational evaluation of the long-term effects of the investigational therapy.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This is a long-term follow-up (LTFU) study for people who previously received NTLA-2001, an investigational CRISPR-based gene-editing therapy developed by Intellia Therapeutics. NTLA-2001 is being studied as a treatment for transthyretin amyloidosis (ATTR), a progressive disease where misfolded protein builds up in organs, particularly the heart and nerves. This follow-up study monitors participants for years after dosing to track long-term safety and durability of the gene editing. You may be eligible if: - You previously participated in an Intellia-sponsored clinical trial and received a full or partial dose of NTLA-2001 - You are willing to provide informed consent for this long-term follow-up study You may NOT be eligible if: - There are no exclusion criteria listed for this study — eligibility is determined solely by prior participation in the NTLA-2001 trial Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(4)

Clinical Trial Site

Paris, France

Clinical Trial Site

Auckland, New Zealand

Clinical Trial Site

Umeå, Sweden

Clinical Trial Site

London, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT05697861


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