RecruitingNCT05697861
Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001
Long-Term Follow-Up of Subjects Treated With NTLA-2001
Sponsor
Intellia Therapeutics
Enrollment
72 participants
Start Date
Jul 10, 2023
Study Type
OBSERVATIONAL
Conditions
Summary
This is a follow-up study of subjects who received NTLA-2001 in a previous clinical trial as an observational evaluation of the long-term effects of the investigational therapy.
Eligibility
Min Age: 18 Years
Plain Language Summary
Simplified for easier understanding
This is a long-term follow-up (LTFU) study for people who previously received NTLA-2001, an investigational CRISPR-based gene-editing therapy developed by Intellia Therapeutics. NTLA-2001 is being studied as a treatment for transthyretin amyloidosis (ATTR), a progressive disease where misfolded protein builds up in organs, particularly the heart and nerves. This follow-up study monitors participants for years after dosing to track long-term safety and durability of the gene editing.
You may be eligible if:
- You previously participated in an Intellia-sponsored clinical trial and received a full or partial dose of NTLA-2001
- You are willing to provide informed consent for this long-term follow-up study
You may NOT be eligible if:
- There are no exclusion criteria listed for this study — eligibility is determined solely by prior participation in the NTLA-2001 trial
Talk to your doctor to see if this trial is right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Locations(4)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05697861