RecruitingNCT05699213
MRI and Biomarkers for Lung Nodules Detected During Lung Cancer Screening
A Pilot Study Evaluating the Feasibility of Novel MRI Sequences and Blood-Based Biomarkers for Discriminating Nodules Found During Lung Cancer Screening
Sponsor
Cedars-Sinai Medical Center
Enrollment
30 participants
Start Date
Jun 27, 2023
Study Type
OBSERVATIONAL
Conditions
Summary
The primary objective of this pilot observational study is to evaluate the accrual and retention rate of a study population from a centralized lung cancer screening program to support MRI and blood-based biomarker research for lung cancer screening.
Eligibility
Min Age: 50 Years
Inclusion Criteria3
- Ability to read and understand informed consent
- Male or female adults who are at high risk for lung cancer and are enrolled in the centralized lung cancer screening program: Based on USPSTF guidelines: Age 50-80 with 20 or greater pack-year smoking story who continue to smoke or quit within the past 15 years without sign or symptoms of lung cancer. Or based on National Comprehensive Cancer Network (NCCN) guidelines but do not meet the USPSTF guidelines, age 50-unlimited
- Found to have one or more lung nodules that is 6mm or greater on screening LDCT
Exclusion Criteria7
- Persons with an active diagnosis of cancer
- Persons with active signs or symptoms of lung cancer
- Persons with mechanically, magnetically, or electrically activated implants, such as cardiac pacemakers, neurostimulators, and infusion pumps.
- Persons with ferromagnetic implants and ferromagnetic foreign bodies, such as intracranial aneurysm clips, shrapnel and intraocular metal chips as these could become dislodged.
- Persons who are pregnant, nursing, are implanted with intrauterine devices (IUD's) that are not MR-compatible
- Persons unable to tolerate MRI imaging secondary to an inability to lie supine or severe claustrophobia.
- Persons who are non-compliant with visit instructions, including inability to lie still, hold breath or follow procedure instructions
Interventions
DIAGNOSTIC_TESTLung MRI
MRI of the lung
DIAGNOSTIC_TESTBlood Draw
Blood Draw
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05699213
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