RecruitingNot ApplicableNCT06618599

Mid-transverse Process Combined With Erector Spinae Block Versus Paravertebral Plane Block

Analgesic Effect of Mid-transverse Process to Pleura Block Combined With Erector Spinae Block Versus Paravertebral Plane Block in Thoracic Surgery for Lung Cancer Patients


Sponsor

Cairo University

Enrollment

60 participants

Start Date

Oct 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to compare efficacy of Mid-transverse process to pleura block combined with erector spinae block versus paravertebral plane block in cancer patients undergoing thoracotomy surgeries.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria4

  • lung cancer patients for thoracotomy surgeries.
  • Physical status American Society of Anesthesiologists (ASA )II, III.
  • Age ≥ 18 and ≤ 65 Years.
  • Body mass index (BMI): \> 20 kg/m2 and \< 35 kg/m2

Exclusion Criteria8

  • Patient refusal
  • physical status ASA IV,
  • Age \<18 years or \>65 years
  • BMI \< 20 kg/m2 and \>35 kg/m2
  • Known sensitivity or contraindication to drug used in the study (local anesthetics, opioids).
  • History of psychological disorders and/or chronic pain.
  • Contraindication to regional anesthesia e.g., local sepsis, pre- existing peripheral neuropathies, and coagulopathy.
  • Severe respiratory, cardiac, hepatic or renal disease.

Interventions

PROCEDUREMid-transverse process to pleura block combined with erector spinae block

The probe will be placed vertically 3 cm lateral to the T5 spinous process and the transverse process will be identified. The needle will be introduced in an in-plane fashion until the tip lay deep in the erector spinae muscle. One milliliter of normal saline will be injected to confirm the correct needle tip position by visualizing the spread under the erector spinae muscle. 20 mL of 0.25% bupivacaine will be injected .The needle will be directed aiming for the midpoint between the transverse process and pleura from cephalad to caudad. One milliliter of normal saline will be given to confirm the position of the needle tip, then a total of 20 ml of 0.25% ropivacaine will be injected

PROCEDUREparavertebral block

the transducer will be positioned laterally 3 cm to the midline at T5 spinous process, defining the spinous process, pleura, transverse process, the paravertebral (PV) space, and superior costotransverse ligament. The trapezius, rhomboid major, and erector spinae muscles will be recognized as superficial to the hyperechoic transverse process shadow. However, when the rhomboid major muscle disappeared, this indicated that we will be at the 7th thoracic vertebra's level. Local infiltration using 2-3 mL of 2.0% lignocaine will be done. A spinal 22-gauge needle will be injected at the cephalic side of the transducer using an in-plane technique, and the needle directed towards the costotransverse ligament (CTL). The passage of the needle through the CTL will be associated with a pop, informing that the superior costotransverse ligament will be passed. Following a 3 mL testing dose of normal saline containing epinephrine (1:200,000), 30 mL bupivacaine 0.25% injected.


Locations(1)

Cairo University

Cairo, Egypt

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NCT06618599


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