RecruitingNCT05700682

Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee

Perfusion MRI-targeted Joint Embolization to Diagnose and Treat Neovascularity Associated With Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee: A Prospective Cohort Study


Sponsor

Palo Alto Veterans Institute for Research

Enrollment

120 participants

Start Date

Jul 15, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

In this work the investigators will study the relationship between chronic musculoskeletal pain and abnormal blood flow (neovascularity) around the shoulder, hip and knee. Veterans with as history of chronic shoulder, hip or knee pain and mild/moderate joint degenerative changes will be potential study subjects. Blood flow around joints will be evaluated using perfusion magnetic resonance imaging (MRI). Participants with demonstrably abnormal blood flow around their painful joint will be eligible for enrollment in a pilot study of joint embolization to treat their pain. Participants who choose to not undergo treatment will be re-assessed with MRI after one year to characterize the natural history of joint neovascularity and its relationship to pain.


Eligibility

Min Age: 25 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Shoulder/Hip/Knee Embolization with Embozene Microspheres for people with osteo arthritis shoulders, osteoarthritis, hip, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 25 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEShoulder/Hip/Knee Embolization with Embozene Microspheres

Fluoroscopically-guided arterial embolization of synovitis in the painful shoulder, hip or knee.


Locations(1)

VA Palo Alto Healthcare System

Palo Alto, California, United States

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NCT05700682


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