RecruitingPhase 2NCT05700825

Rehabilitation of Airway Protection in Parkinson's Disease

Rehabilitation of Airway Protection in Parkinson's Disease: Comparing In-person and Telehealth Service Delivery Models

Sponsor

Teachers College, Columbia University

Enrollment

120 participants

Start Date

Aug 11, 2022

Study Type

INTERVENTIONAL

Conditions

Parkinson Disease Dysphagia

Summary

Airway protective disorders are a prevalent and progressive consequence of Parkinson's Disease (PD), and often result in aspiration pneumonia which is the leading cause of death in PD. Despite this, a large number of patients with PD do not access specialized services to address these critical deficits. The investigators will examine the comparative effectiveness of a novel treatment paradigm delivered in-person versus via telehealth in persons with PD, as well as the role of patient burden and treatment adherence on outcomes; thus, the proposed research is relevant to public health and in line with NIH's mission to identify novel, efficacious, and accessible rehabilitation strategies for short- and long-term improvement of dysfunctional airway protection in PD.

Eligibility

Min Age: 50 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study tests rehabilitation exercises for people with Parkinson's disease who have difficulty swallowing safely and/or a weakened cough — two problems that increase the risk of choking and aspiration pneumonia. The goal is to improve airway protection through targeted therapy. **You may be eligible if...** - You are 50–90 years old with a confirmed Parkinson's disease diagnosis (Hoehn and Yahr stages II–IV) - You have been found to have swallowing problems (liquid entering the airway) or a weak cough on testing - You are not currently in swallowing therapy **You may NOT be eligible if...** - You have another neurological condition (e.g., multiple sclerosis, stroke, brain tumor) - You have a history of head and neck cancer or radiation to the head/neck - Your Parkinson's disease is too advanced to safely participate in rehabilitation exercises Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BEHAVIORALExpiratory Muscle Strength Training + Cough Skill Training

Expiratory Muscle Strength Training (EMST). EMST is a widely used and efficacious treatment approach that uses a calibrated device with a one-way, spring-loaded pressure relief valve to mechanically overload the expiratory and submental muscles. Cough Skill Training (CST) involves a digital peak flow meter device which measures PEFR (peak expiratory flow rate) in liters/second and allows patients to receive immediate biofeedback.

Locations(2)

Purdue University

West Lafayette, Indiana, United States

Teachers College, Columbia University

New York, New York, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05700825

Related Trials

The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States

NCT070278263 locations

The University of Alabama at Birmingham (UAB) Neuroinflammation in Parkinson's Disease-TSPO- Positron Emission Tomography (PET) Substudy

NCT034574931 location