RecruitingNCT05703516

A Post Approval Commitment Study on Tabrecta® (Capmatinib) in South Korea

A Post Approval Commitment Study on Tabrecta® (Capmatinib) in South Korea; Open Label, Prospective, Multicenter, Post Approval Surveillance


Sponsor

Novartis Pharmaceuticals

Enrollment

250 participants

Start Date

Jun 12, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This is an open label, prospective, multicenter, non-comparative study to assess the safety and effectiveness of Tabrecta® (Capmatinib) in real world setting. Also, this study is to fulfill the regulatory requirements as part of the RMP (Risk Management Plan) for Tabrecta® (Capmatinib), as requested by Korea Health Authority, MFDS (Ministry of Food and Drug Safety).


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria3

  • Signed informed consent must be obtained prior to participation in the study.
  • Subject who are diagnosed as exon 14 skipping mutated NSCLC from tissue or plasma(ctDNA) sample analysis by treating physician (i.e. Any kind of diagnostic methods the institution currently has. Diagnostic modalities for research purpose would be also allowable.)
  • Subject who plan to receive Tabrecta® (Capmatinib) as per locally approved label

Exclusion Criteria3

  • Subject with contraindication according to the locally approved label
  • Subject whose medical record is not accessible
  • Subject who are not willing to provide informed consent

Interventions

OTHERCapmatinib

There is no treatment allocation. Capmatinib will be prescribed by the physician as per locally approved label. Treatment duration depends on the decision of treating physician. No drug will be dispensed from Novartis


Locations(12)

Novartis Investigative Site

Daegu, Dalseo Gu, South Korea

Novartis Investigative Site

Suwon, Gyeonggi-do, South Korea

Novartis Investigative Site

Seoul, Korea, South Korea

Novartis Investigative Site

Seoul, Seocho Gu, South Korea

Novartis Investigative Site

Busan, South Korea

Novartis Investigative Site

Daejeon, South Korea

Novartis Investigative Site

Incheon, South Korea

Novartis Investigative Site

Jeollanam, South Korea

Novartis Investigative Site

Seoul, South Korea

Novartis Investigative Site

Seoul, South Korea

Novartis Investigative Site

Seoul, South Korea

Novartis Investigative Site

Seoul, South Korea

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NCT05703516


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