RecruitingNCT05706532

Cardiovascular and Cerebrovascular Control in Healthy Subjects

Cardiovascular and Cerebrovascular Control in Healthy Adult Subjects


Sponsor

IRCCS Policlinico S. Donato

Enrollment

60 participants

Start Date

May 29, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of the study is to evaluate autonomic function and cerebrovascular control in 60 healthy subjects by means of noninvasive analysis of time series variability. To this extent, heart period, systolic and mean arterial blood pressure, cerebral blood velocity, peripheral resistances, respiration will be recorded from subjects during an orthostatic challenge. The interactions between autonomic cardiovascular function, cerebrovascular and peripheral control will be evaluated exploiting the most advanced signal processing techniques.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • age >18
  • sinus rhythm
  • informed consent signed

Exclusion Criteria2

  • age <18
  • presence of autonomic nervous system diseases or dysfunctions

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Interventions

DIAGNOSTIC_TESTactive standing

Data are acquired with patients resting in supine position for 10 minutes and for 10 minutes during active standing


Locations(1)

IRCCS Policlinico San Donato

San Donato Milanese, Milan, Italy

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NCT05706532


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