RecruitingNot ApplicableNCT05706766

Prehabilitation Exercise Training in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation

Prehabilitation Exercise Training in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation: The PROTECT Trial

Sponsor

Dana-Farber Cancer Institute

Enrollment

30 participants

Start Date

Jun 29, 2023

Study Type

INTERVENTIONAL

Conditions

Multiple Myeloma Stem Cell Transplant Complications

Summary

The goal of this research study is to investigate whether a virtual, home-based, prehabilitation aerobic and resistance exercise (PARE) training program implemented 8 weeks prior to receiving autologous stem cell transplant (ASCT) for multiple myeloma participants will improve muscular strength, physical capacity, patient reported outcomes, and cardiometabolic health outcomes. The names of the study interventions involved in this study are: * Prehabilitative aerobic and resistance exercise (PARE) (virtually supervised 8-week aerobic and resistance exercise program) * Waitlist control (8-week normal activity behavior)

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a structured exercise program (prehabilitation) before stem cell transplantation in multiple myeloma patients. The goal is to see whether getting physically stronger and fitter before the transplant helps patients recover better afterward. **You may be eligible if...** - You are over 18 years old and have a diagnosis of multiple myeloma - You are scheduled to have your first autologous stem cell transplant at Dana-Farber Cancer Institute in at least 8 weeks - You have been cleared by your doctor to do moderate-to-vigorous exercise - You currently exercise less than 60 minutes per week - You speak English and can travel to Dana-Farber for study visits **You may NOT be eligible if...** - You have had a heart attack or unstable heart condition in the past month - You have other medical conditions that prevent safe exercise participation - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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