RecruitingPhase 4NCT05709626

PRasugrEl Monotherapy Following prImary percUtaneous Coronary Intervention for ST-elevation Myocardial Infarction


Sponsor

Kindai University

Enrollment

2,258 participants

Start Date

Feb 28, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this study is to evaluate the safety of prasugrel monotherapy without aspirin versus 12-month dual antiplatelet therapy (DAPT) in patients with STEMI using platinum-chrome everolimus-eluting stent (PtCr-EES: SYNERGYTM).


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Patients scheduled for primary PCI with everolimus-eluting stent (PtCr-EES, SYNERGYTM)
  • STEMI patients
  • Patients who can continue dual antiplatelet therapy with aspirin and a P2Y12 inhibitor for 12 months

Exclusion Criteria4

  • Patients taking anticoagulants
  • Patients under 18 years old
  • Patients with less than 1 year prognosis
  • Patients participating in other intervention studies

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Interventions

DRUGNo aspirin (Prasugurel monotherapy)

12-month prasugrel monotherapy

DRUG12-month DAPT

12-month dual antiplatelet therapy with prasugrel and aspirin


Locations(1)

Kindai University Faculty of Medicine

Sayama, Osaka, Japan

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NCT05709626


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