RecruitingNot ApplicableNCT05711485

Platelet-Directed Whole Blood Transfusion Strategy for Malaria

Clinical and Translational Investigations of Severe Malaria Pathophysiology [Parent Study Protocol]


Sponsor

Johns Hopkins Bloomberg School of Public Health

Enrollment

132 participants

Start Date

Feb 24, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Open-label randomized controlled trial to test the effectiveness of whole blood transfusion for improving survival in children with severe malaria complicated by thrombocytopenia.


Eligibility

Min Age: 6 MonthsMax Age: 59 Months

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Whole blood transfusion for people with severe malaria and thrombocytopenia. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 6 Months to 59 Months.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERWhole blood transfusion

Whole blood is sourced from the Zambia National Blood Transfusion Service.


Locations(2)

Johns Hopkins Bloomberg School of Public Health

Baltimore, Maryland, United States

Tropical Diseases Research Centre

Ndola, Copperbelt, Zambia

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NCT05711485


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