Aortic Stiffness in Patients With Genetic Aortopathies
Aortic Stiffness in Patients With Genetic Aortopathies: Intervention Analysis
IRCCS Policlinico S. Donato
250 participants
Feb 15, 2023
OBSERVATIONAL
Conditions
Summary
The goal of this observational study is to study arterial stiffness in patients with thoracic ascending aortic aneurysms (TAA), either syndromic or non-syndromic. The main questions it aims to answer are: * Stratification of aortic risk based on arterial stiffness; Compare measurements with morphological and haemodynamic features of the ascending thoracic aorta. Participants will be asked to undergo non-invasive evaluation of blood pressure and arterial stiffness.
Eligibility
Inclusion Criteria2
- Subjects with AAT, either syndromic or non syndromic;
- Signed informed consent
Exclusion Criteria4
- Patients with early menopause and/or osteoporosis, rheumatic heart disease and active malignant tumours;
- Patients with acute and chronic inflammatory conditions such as: chronic liver disease, chronic renal insufficiency and diseases affecting the thyroid system;
- Seropositivity to HIV, HCV, HBsAg and SARS-CoV-2;
- Pregnancy
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Evaluation of arterial stiffness
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05715203