RecruitingNCT05718791

CXCL9 and EASIX for Prediction of Acute Graft Versus Host Disease

CXC-chemokine Ligand 9 (CXCL9) and Endothelial Activation and Stress Index (EASIX) for Prediction of Acute Graft Versus Host Disease


Sponsor

Henry Ford Health System

Enrollment

100 participants

Start Date

May 10, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The prediction of severe acute GVHD before it occurs is of high importance for ensuing clinical decisions and overall success of allogeneic SCT. The key immunologic signatures associated with clinical outcomes after different graft versus host disease prophylaxis methods or peripheral blood stem cell transplant are largely unknown.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria1

  • Patients >18 year old admitted for allo SCT PB for malignant disease.

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Interventions

DIAGNOSTIC_TESTblood sample

blood sample to check CXCL9 and EASIX at day 28 post stem cell transplant


Locations(1)

Henry Ford Health System

Detroit, Michigan, United States

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NCT05718791


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