RecruitingNCT05722275

Prediction of Peritoneal Metastasis for Gastric Cancer Based on Radiomics

Prediction of Peritoneal Metastasis for Gastric Cancer Based on Radiomics: a Multi-center Prospective Study


Sponsor

Chinese Academy of Sciences

Enrollment

400 participants

Start Date

Jan 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Peritoneal metastasis of gastric cancer is difficult to be detected in time, thus delaying treatment. Based on the conventional CT images of gastric cancer, this study plans to develop, improve and validate an intelligent analysis system based on radiomics. By extracting and combining the radiomics features related to peritoneal metastasis of gastric cancer, the intelligent analysis system could predict the risk of peritoneal metastasis, and provide personalized decision suggestions for the treatment of gastric cancer.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is using a technique called radiomics — where artificial intelligence analyzes patterns in CT scan images — to predict whether advanced gastric cancer has already spread to the inner lining of the abdomen (peritoneal metastasis) before surgery, helping doctors plan treatment more accurately without always needing a laparoscopy. **You may be eligible if...** - You have been diagnosed with locally advanced gastric cancer (stage cT3 or higher) confirmed by endoscopy and biopsy - You have had both a CT scan and a laparoscopy (keyhole abdominal exploration) - Your CT scan does not already show obvious signs of widespread peritoneal spread - Your CT scan and laparoscopy were done within 2 weeks of each other **You may NOT be eligible if...** - You have had previous abdominal surgery or prior abdominal cancer - There was more than 2 weeks between your CT scan and laparoscopy - Your CT images have significant quality issues preventing analysis Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DIAGNOSTIC_TESTPeritoneal metastasis status ascertainment

Each participant with gastric cancer will undergo enhanced CT examination for detection of peritoneal metastasis. Within two weeks of CT examination, the participant will undergo diagnostic laparoscopy to confirm the status of peritoneal metastasis.


Locations(13)

Peking University Cancer Hospital & Institute

Beijing, China

Fujian Medical University Union Hospital

Fuzhou, China

Affiliated Cancer Hospital and Institute of Guangzhou Medical University

Guangzhou, China

Guangdong Provincial People's Hospital

Guangzhou, China

Nanfang Hospital of Southern Medical University

Guangzhou, China

Sun Yat-Sen University Cancer Hospital

Guangzhou, China

Guizhou Provincial People's Hospital

Guiyang, China

Yunnan Cancer Hospital

Kunming, China

Shanxi Province Cancer Hospital

Taiyuan, China

Henan Cancer Hospital

Zhengzhou, China

The First Affiliated Hospital of Zhengzhou University

Zhengzhou, China

Zhenjiang First People's Hospital

Zhenjiang, China

Scientific Institute San Raffaele

Milan, Italy

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05722275


Related Trials