RecruitingNot ApplicableNCT05722873

The Metabolic Effects of Intermittent Fasting

The Effects of Fasting on Reprogramming of Lipid Metabolism and Bone Metabolism

Sponsor

University of Pittsburgh

Enrollment

90 participants

Start Date

Oct 25, 2023

Study Type

INTERVENTIONAL

Conditions

Normal and Overweight Individuals at High-risk of Diabetes

Summary

Caloric restriction has beneficial metabolic effects in humans including weight loss and improvement in blood pressure and lipid levels. Intermittent fasting has emerged as a popular alternative to caloric restriction as it does not require daily adherence to a dietary protocol, but whether the benefits of fasting protocols are dependent on weight loss is not known. In this study, the investigators will explore the metabolic effects of fasting and evaluate whether these effects, including negative effects on bone metabolism, are independent of weight loss.

Eligibility

Min Age: 21 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Counseling, a behavioral approach called Fasting arm, and others for people with normal and overweight individuals at high-risk of diabetes. The study is currently recruiting participants at 1 location. People eligible for this study include aged 21 Years to 45 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALFasting arm

Study participants will fast one day per week for 12 weeks

BEHAVIORALWeight maintenance

Study participants will be counseled to maintain body weight

BEHAVIORALCounseling

Study participants will be counseled on optimal diet and activity recommendations for maintaining/achieving a normal BMI

Locations(1)

University of Pittsburgh

Pittsburgh, Pennsylvania, United States

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NCT05722873