A Study of the Clinical Efficacy and Safety of 20% Cassia Alata Extract Against Tinea Versicolor
A Single Arm No-treatment Self-controlled Trial Pilot Study Evaluating the Clinical Efficacy and Safety Profile of 20% Cassia Alata Cream Against Tinea Versicolor
The University of The West Indies
20 participants
Mar 1, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to establish the efficacy of Cassia alata extract as a cream form in treating tinea versicolor (liver spots/shifting clouds). The main questions the study aims to answer are:• Does the use of this extract help resolve tinea versicolor better than no treatment? Does the use of this cream have significant side effects i.e, is it safe? Participants will be asked to treat a designated area while leaving additional areas untreated. 1-2 finger tip units of cream will be applied to the treatment site twice daily at least 8 hours apart. Participants will attend the trial clinic every 4 weeks for 12 weeks.
Eligibility
Inclusion Criteria6
- Patients aged 18-89 of either sex
- Clinical features suggestive of tinea versicolor AND Microscopic confirmation using skin scraping stains with chlorazol black preparation AND/OR Wood's lamp fluorescence
- No treatment for versicolor in the preceding 4 weeks
- No contraindications to the application of C.alata cream including
- No history of allergy to C. alata
- No history of preservative allergy
Exclusion Criteria5
- Age <18 or >89 years
- Pregnant females
- History of hypersensitivity to C. alata or preservative
- Treatment within 4 weeks prior to enrollment
- Lesions which do not meet the diagnostic criteria of tinea versicolor
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Thin layer of cassia alata cream to cover treatment area. 1 finger tip unit will cover roughly 4 x 4 inch area. Number of FTU determined by investigators depending on rough size of area to be treated
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05730244