RecruitingNot ApplicableNCT05734222

Optimization of Surgical Treatment of Patients With Incisional Ventral Hernias

Optimization of Surgical Treatment of Patients With Postoperative Median and Median-lateral Ventral Hernias


Sponsor

Samara State Medical University

Enrollment

110 participants

Start Date

Sep 29, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of our work of optimization of the treatment of postoperative hernias is to improve the results of treatment of patients with median and median-lateral postoperative hernias of medium (W2) and large (W3) sizes by developing new surgical techniques. The main questions it aims to answer are: 1. To study the topographic and variant anatomy of vessels and nerves in the retromuscular, preperitoneal, postperitoneal and pre-abdominal cell spaces of the anterior abdominal wall. To determine the most probable sources of blood flow and lymph from the anatomical formations forming the bed of the endoprosthesis. 2. To develop technical, surgical techniques that allow to form an implant bed with minimal traumatization of blood vessels and nerves and reduce the risk of postoperative complications. 3. To develop a technique for plasty of the anterior abdominal wall in mid-lateral postoperative hernias with a combination of retromuscular and subaponeurotic spaces. The researchers will compare an experimental group in which a new method of preparing the implant place will be used and a control group in which standard methods of treating postoperative ventral hernias were used to see whether the new method affects the improvement of the postoperative period and the reduction of complications.


Eligibility

Min Age: 25 YearsMax Age: 88 Years

Plain Language Summary

Simplified for easier understanding

Incisional ventral hernias — where abdominal organs protrude through weaknesses in the abdominal wall at the site of a previous surgical incision — are a common complication of abdominal surgery, affecting up to 20% of patients who have had laparotomies. Surgical repair is the only definitive treatment, but there is no consensus on the best approach for medium-sized hernias (width 4.1 to 15 cm), and recurrence rates remain high. This study compares different surgical repair techniques — including mesh placement strategies and component separation methods — to identify the most effective approach for optimizing long-term outcomes. Patients between 25 and 88 years of age with postoperative ventral hernias of median or lateral localization with a gate width of 4.1 to 15 cm (classified as W2-W3 by the European Hernia Society), as confirmed by CT scan, are eligible. Patients without a postoperative ventral hernia or outside this size range are not included. Participants will undergo their hernia repair surgery using one of the compared techniques and be followed post-operatively for recurrence rates, complications, recovery time, and quality of life. This research is important because hernia recurrence — where the repaired hernia comes back — is a significant problem that often requires additional surgery, prolongs recovery, and greatly impacts quality of life. Identifying the optimal surgical technique for this hernia size category could reduce recurrence rates and spare patients from repeat operations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREA new method of repair of the abdominal wall of mid-lateral postoperative ventral hernias

1. It is planned to study potential sources of bleeding and hematoma formation during SRM plastic surgery. On this basis, recommendations on the technique of the operation will be formulated. 2. It is supposed to find a way to preserve intercostal neurovascular bundles when performing SRM repair. This should improve the quality of abdominal wall reconstruction by preserving neurovascular bundles of muscles and reducing neuroalgic pain syndrome. 3. It is proposed to develop a method for combining retromuscular and subaponeurotic spaces in the treatment of mid-lateral hernias 4. It is planned to substantiate the effectiveness and expediency of the application of the developed surgical techniques based on the analysis of the immediate and long-term results of treatment.


Locations(1)

Clinics of Samara State Medical University

Samara, Russia

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NCT05734222


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