A Retrospective Assessment of OviTex PRS (OviTex)

This study retrospectively — and in some cases prospectively — evaluates the outcomes of breast reconstruction using the OviTex PRS mesh, a biological and synthetic composite material used to support breast tissue after mastectomy. When a patient has a breast implant placed after cancer surgery, surgical mesh is often used to support the implant and improve results. OviTex is a newer option and this study aims to gather real-world data on its safety, complication rates, and patient satisfaction outcomes. Women aged 18 to 75 who underwent implant-based breast reconstruction using a specific OviTex PRS product are eligible. Women who received a textured permanent breast implant, were nicotine users within four weeks of surgery, or had prior radiation therapy to the chest wall are excluded. For the prospective portion, participants must be able to return for follow-up visits. For retrospective participants, data is collected from existing medical records. Prospective participants attend follow-up visits and may have photographs taken. No experimental treatment is involved. This study is important because choosing the right mesh material in breast reconstruction affects complication rates (including infection and implant failure) and long-term cosmetic outcomes — and real-world evidence helps surgeons and patients make better-informed decisions.