Efficacy of SynEx Wound Rinse in Civilian Surrogates of Combat Injury Wounds

This study is testing a wound rinse solution called SynEx for treating traumatic wounds in civilian patients — wounds that mimic the kinds of injuries seen in military combat settings, including lacerations, punctures, gunshot wounds, and partial-thickness burns. Wound infection is a major complication of traumatic injuries, and effective irrigation and cleaning solutions are essential to reduce bacterial contamination and promote healing. SynEx is being evaluated for its safety and effectiveness compared to standard wound care. Eligible participants must be 18 years or older with acute penetrating, puncture, gunshot, or burn wounds of the arms or legs that meet specific severity criteria, and be seen within 72 hours of the injury. Pregnant or lactating women, patients requiring surgical debridement in an operating room, those with serious secondary injuries (like traumatic brain injury or sepsis), or those with known allergies to study components are excluded. This research is significant because wound care is one of the most fundamental yet consequential aspects of trauma management. Inadequate wound cleaning increases the risk of infection, tissue loss, and in severe cases, amputation or death. A superior wound rinse solution could benefit emergency rooms, military field medicine, and disaster response settings — improving outcomes for millions of trauma patients globally, particularly in resource-limited environments where infection control options are limited.