RecruitingNot ApplicableNCT05743374

Micronutrient and Additive Modifications May Optimize Diet To Health


Sponsor

Region Skane

Enrollment

70 participants

Start Date

Apr 2, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This is a prospective clinical intervention trial where patients with moderately active ulcerative colitis are randomized to either normal healthy diet or a diet with elimination of emulsifying agents within the E 400-group with special respect to carragenan, CMC and polysorbates. At study start and end after one month their diet, clinical characteristics and microbiota will be analysed. The hypotheses are that their disease activity measured with calprotectin and their microbiota will improve after intervention.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is examining whether making specific changes to micronutrients and food additives in the diet can help manage moderately active ulcerative colitis (a chronic inflammatory bowel disease causing colon inflammation and diarrhea). **You may be eligible if...** - You have been diagnosed with ulcerative colitis - Your disease is moderately active - You are on stable medication for your UC **You may NOT be eligible if...** - Your ulcerative colitis is severe - You have had recent bowel surgery - Your disease is limited to the rectum only (proctitis) - You are pregnant - You are currently on antibiotics - You have difficulty understanding the study information - You have multiple serious health conditions that make participation unsafe Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERNormal diet

These patients will be given advice about a normal healthy diet.

DIETARY_SUPPLEMENTE400 elimination

Patients in the intervention group will be given advice how to eliminate E440 additives with regard to carragenan, CMC and polysorbates.


Locations(1)

Region Skåne

Malmö, Skåne County, Sweden

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NCT05743374


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