RecruitingNot ApplicableNCT05743374

Micronutrient and Additive Modifications May Optimize Diet To Health


Sponsor

Region Skane

Enrollment

70 participants

Start Date

Apr 2, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This is a prospective clinical intervention trial where patients with moderately active ulcerative colitis are randomized to either normal healthy diet or a diet with elimination of emulsifying agents within the E 400-group with special respect to carragenan, CMC and polysorbates. At study start and end after one month their diet, clinical characteristics and microbiota will be analysed. The hypotheses are that their disease activity measured with calprotectin and their microbiota will improve after intervention.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Ulcerative colitis,
  • Moderately active
  • Stable medication

Exclusion Criteria7

  • Severe disease
  • Recent surgery
  • Proctitis
  • Pregancy
  • Treatment with antibiotics
  • Difficulties in understanding the information about the study
  • Multimorbidity that makes it impossible to participate

Interventions

OTHERNormal diet

These patients will be given advice about a normal healthy diet.

DIETARY_SUPPLEMENTE400 elimination

Patients in the intervention group will be given advice how to eliminate E440 additives with regard to carragenan, CMC and polysorbates.


Locations(1)

Region Skåne

Malmo, Skåne County, Sweden

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NCT05743374


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